TY  - JOUR
ID  - 6368
A1  - Abend,N. S.
A1  - Dlugos,D. J.
T1  - Nonconvulsive Status Epilepticus in a Pediatric Intensive Care Unit
Y1  - 2007
Y2  - Sep
VL  - 37
IS  - 3
SP  - 165
EP  - 170
AB  - We aimed to describe nonconvulsive status epilepticus in terms of patient age, etiology, initial presentation, and electroencephalogram and neuroimaging findings. Twenty children with nonconvulsive status epilepticus were identified by a retrospective review of children who underwent long-term electroencephalogram monitoring in a pediatric intensive care unit. Age ranged from 2 months to 18 years, and in 30% of patients, the age was <1 year. Nonconvulsive status epilepticus occurred most commonly in children with prior epilepsy (35%) or congenital heart disease (25%). Prior to nonconvulsive status epilepticus, most had experienced isolated seizures (55%) or convulsive status epilepticus (20%), but some had only preceding mental-status change (25%). The most common etiologies were exacerbation of epilepsy (35%) and ischemic stroke (25%). No children aged <1 year had preexisting epilepsy. Electroencephalograms confirmed nonconvulsive status epilepticus immediately in 65%. Nonconvulsive status epilepticus lasted up to 8 days, and neuroimaging was abnormal in 82% of patients. Nonconvulsive status epilepticus occurs in a heterogeneous group of children, results from acute symptomatic etiologies in children aged <1 year, most frequently follows isolated convulsions but can occur with only preceding mental status change, and is often prolonged. These findings suggest that a high level of suspicion for nonconvulsive status epilepticus must be maintained, and long-term electroencephalogram monitoring may be indicated in a large number of patients.
N1  - PUBM: Print; JID: 8508183; 2007/02/13 [received]; 2007/04/25 [revised]; 2007/05/25 [accepted]; ppublish
A3  - Anonymous
SN  - 0887-8994
AD  - Division of Neurology, Children's Hospital of Philadelphia, and Department of Neurology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania.
JF  - Pediatric neurology
JA  - Pediatr.Neurol.
M1  - Journal
ER  - 

TY  - JOUR
ID  - 6392
A1  - Akanji,A. O.
A1  - Suresh,C. G.
A1  - Al-Radwan,R.
A1  - Fatania,H. R.
T1  - Insulin-like growth factor (IGF)-I, IGF-II and IGF-binding protein (IGFBP)-3 levels in Arab subjects with coronary heart disease
Y1  - 2007
VL  - 67
IS  - 5
SP  - 553
EP  - 559
AB  - Objective . Insulin-like growth factors (IGF-I, IGF-II) and their binding protein (IGFBP-3) may be risk markers for coronary heart disease (CHD). This study aimed to assess the levels and determinants of the serum levels of IGF-I, IGF-II and IGFBP-3 in Arab patients with established CHD. Material and methods . Two groups of subjects were matched for age, gender, BMI and waist-hip ratio (WHR): (i) CHD (n = 105), median age 51.0 (range 40.0-60.0) years; (ii) controls (n = 97) aged 49.0 (range 37.0-60.0) years. We measured fasting serum levels of glucose and lipoproteins (total cholesterol, triglycerides, LDL, HDL, apo B), insulin, HOMA-IR, IGF-I, IGF-II and IGFBP-3 and compared the results between groups. The effects of body mass and the metabolic syndrome (MS) on IGF levels were also examined, and linear correlations were sought between the various parameters. Results . The levels of IGF-I, IGF-II and IGFBP-3 were significantly lower (all p<0.01) for the CHD group than for the control group. These differences were not influenced by BMI or with the presence of MS. In CHD, there were no significant correlations between levels of IGF-I and IGF-II and age, BMI, WHR, lipoprotein concentrations and insulin sensitivity, although IGFBP-3 had weakly significant relationships with some of the lipoproteins. Conclusions . Levels of IGF-I, IGF-II and IGFBP3 are reduced in male Arab patients with CHD, and did not appear influenced by traditional CHD risk factors such as age, BMI, insulin sensitivity and presence of MS. Perturbations in the IGF/IGFBP-3 axis may be potential additional targets for pharmacological manipulation in CHD.
N1  - PUBM: Print; JID: 0404375; ppublish
CY  - Norway
A3  - Anonymous
SN  - 0036-5513
AD  - Departments of Pathology.
JF  - Scandinavian journal of clinical and laboratory investigation
JA  - Scand.J.Clin.Lab.Invest.
M1  - Journal
ER  - 

TY  - BOOK
ID  - 6325
A1  - Atkinson,John W.
T1  - An introduction to motivation
Y1  - 1964
SP  - 335
KW  - Motivation (Psychology)
N1  - by John W. Atkinson.; Bibliography: p. 315-324.
T2  - The University series in psychology
PB  - Van Nostrand
CY  - Princeton, N. J.
A3  - Anonymous
M1  - Book, Whole
ER  - HATCH GRAD BF 683 .A87

TY  - BOOK
ID  - 6327
A1  - Atkinson,John W.
T1  - An introduction to motivation
Y1  - 1964
SP  - 335
KW  - Motivation (Psychology)
N1  - by John W. Atkinson.; Bibliography: p. 315-324.
T2  - The University series in psychology
PB  - Van Nostrand
CY  - Princeton, N. J.
A3  - Anonymous
M1  - Book, Whole
ER  - FLINT MAIN BF683.A8 I6

TY  - BOOK
ID  - 6331
A1  - Atkinson,John W.
T1  - An introduction to motivation
Y1  - 1964
SP  - 335
KW  - Motivation (Psychology)
N1  - by John W. Atkinson.; Bibliography: p. 315-324.
T2  - The University series in psychology
PB  - Van Nostrand
CY  - Princeton, N. J.
A3  - Anonymous
M1  - Book, Whole
ER  - HATCH GRAD BF 683 .A87

TY  - BOOK
ID  - 6333
A1  - Atkinson,John W.
T1  - An introduction to motivation
Y1  - 1964
SP  - 335
KW  - Motivation (Psychology)
N1  - by John W. Atkinson.; Bibliography: p. 315-324.
T2  - The University series in psychology
PB  - Van Nostrand
CY  - Princeton, N. J.
A3  - Anonymous
M1  - Book, Whole
ER  - FLINT MAIN BF683.A8 I6

TY  - BOOK
ID  - 6329
A1  - Atkinson,John W.
A1  - Birch,David
T1  - An introduction to motivation
Y1  - 1978
SP  - 405
KW  - Motivation (Psychology)
N1  - John W. Atkinson, David Birch.; Bibliography: p. 381-393.; Includes indexes.
VL  - 2d
PB  - Van Nostrand
CY  - New York
A3  - Anonymous
SN  - 0442203675
M1  - Book, Whole
ER  - FLINT MAIN BF 503 .A83 1978

TY  - BOOK
ID  - 6335
A1  - Atkinson,John W.
A1  - Birch,David
T1  - An introduction to motivation
Y1  - 1978
SP  - 405
KW  - Motivation (Psychology)
N1  - John W. Atkinson, David Birch.; Bibliography: p. 381-393.; Includes indexes.
VL  - 2d
PB  - Van Nostrand
CY  - New York
A3  - Anonymous
SN  - 0442203675
M1  - Book, Whole
ER  - FLINT MAIN BF 503 .A83 1978

TY  - BOOK
ID  - 6324
A1  - Atkinson,John W.
A1  - Raynor,Joel O.
T1  - Motivation and achievement
Y1  - 1974
SP  - 479
KW  - Achievement motivation
N1  - by John W. Atkinson and Joel O. Raynor. In collaboration with David Birch [and others]; Includes bibliography.
PB  - V. H. Winston
CY  - Washington
A3  - Anonymous
SN  - 0470036265
M1  - Book, Whole
ER  - HATCH GRAD BF 683 .A875

TY  - BOOK
ID  - 6328
A1  - Atkinson,John W.
A1  - Raynor,Joel O.
T1  - Motivation and achievement
Y1  - 1974
SP  - 479
KW  - Achievement motivation
N1  - by John W. Atkinson and Joel O. Raynor, in collaboration with David Birch [and others]; "A Halsted Press book."; Bibliography: p. 439-454.
PB  - Winston; distributed by Halsted Press Division, New York
CY  - Washington
A3  - Anonymous
SN  - 0470036265
M1  - Book, Whole
ER  - FLINT MAIN BF683.A8 M6

TY  - BOOK
ID  - 6330
A1  - Atkinson,John W.
A1  - Raynor,Joel O.
T1  - Motivation and achievement
Y1  - 1974
SP  - 479
KW  - Achievement motivation
N1  - by John W. Atkinson and Joel O. Raynor. In collaboration with David Birch [and others]; Includes bibliography.
PB  - V. H. Winston
CY  - Washington
A3  - Anonymous
SN  - 0470036265
M1  - Book, Whole
ER  - HATCH GRAD BF 683 .A875

TY  - BOOK
ID  - 6334
A1  - Atkinson,John W.
A1  - Raynor,Joel O.
T1  - Motivation and achievement
Y1  - 1974
SP  - 479
KW  - Achievement motivation
N1  - by John W. Atkinson and Joel O. Raynor, in collaboration with David Birch [and others]; "A Halsted Press book."; Bibliography: p. 439-454.
PB  - Winston; distributed by Halsted Press Division, New York
CY  - Washington
A3  - Anonymous
SN  - 0470036265
M1  - Book, Whole
ER  - FLINT MAIN BF683.A8 M6

TY  - BOOK
ID  - 6326
A1  - Atkinson,John William
A1  - Birch,David
T1  - An introduction to motivation
Y1  - 1978
SP  - 405
KW  - Motivation (Psychology)
N1  - John W. Atkinson, David Birch.; Bibliography: p. 381-393.
VL  - 2d
PB  - Van Nostrand
CY  - New York
A3  - Anonymous
M1  - Book, Whole
ER  - HATCH GRAD BF 683 .A87 1978; UGL BF 683 .A87 1978 BK

TY  - BOOK
ID  - 6332
A1  - Atkinson,John William
A1  - Birch,David
T1  - An introduction to motivation
Y1  - 1978
SP  - 405
KW  - Motivation (Psychology)
N1  - John W. Atkinson, David Birch.; Bibliography: p. 381-393.
VL  - 2d
PB  - Van Nostrand
CY  - New York
A3  - Anonymous
M1  - Book, Whole
ER  - HATCH GRAD BF 683 .A87 1978; UGL BF 683 .A87 1978 BK

TY  - JOUR
ID  - 6385
A1  - Babikar,A.
A1  - Hynes,B.
A1  - Ward,N.
A1  - Oslizok,P.
A1  - Walsh,K.
A1  - Keane,D.
T1  - A retrospective study of the clinical experience of the implantable loop recorder in a paediatric setting
Y1  - 2007
Y2  - Aug 31
AB  - The implantable loop recorder (ILR) has proved highly efficacious in the management of syncope, presyncope and palpitations in selected populations. Limited information regarding patient selection and diagnostic yield exists in the paediatric setting. A retrospective evaluation of patients who underwent ILR implantation over a 66-month period, in a tertiary paediatric cardiology unit was conducted. Twenty-three patients (10 male, 13 female) following initial assessment and investigation, were referred for device implantation. The mean age at time of ILR insertion was 11.39 +/- 4.34 (range, 2.0-16.8) years. The indications for ILR were recurrent syncope (n = 11), presyncope (n = 3) or palpitations (n = 9). Four (17.4%) patients had structural heart disease, three (13%) had a positive family history of sudden cardiac death and one (4%) had perinatal arrhythmia. One patient required ILR repositioning, and pocket infection necessitated explantation in one further patient. Minimum follow-up was 7.8 months during which symptoms were reported in 15 (65.2%) patients post-ILR insertion. Eight (34.7%) remained asymptomatic. Of the 15 who experienced symptom recurrence, eight (53.3%) had an arrhythmia recorded. Tachycardias recorded were polymorphic ventricular tachycardia (n = 1) and supraventricular tachycardia (n = 5). Clinically significant bradycardias documented, included sinus arrest (n = 1) and Mobitz type II second degree atrioventricular block (n = 1). The ILR had a high diagnostic yield, enabling an arrhythmic or non-arrhythmic diagnosis in 65.2% of patients with recurrent syncope, presyncope or palpitations in a selected paediatric population.
N1  - PUBM: Print-Electronic; DEP: 20070831; JID: 9712381; aheadofprint
A3  - Anonymous
SN  - 1368-5031
AD  - Cardiac Arrhythmia Department, St Vincent's University Hospital, Dublin, Ireland.
JF  - International journal of clinical practice
JA  - Int.J.Clin.Pract.
M1  - Journal
ER  - 

TY  - JOUR
ID  - 6397
A1  - Bai,Y.
A1  - Wang,J.
A1  - Lu,Y.
A1  - Shan,H.
A1  - Yang,B.
A1  - Wang,Z.
T1  - Phospholipid Lysophosphatidylcholine as a Metabolic Trigger and HERG as an Ionic Pathway for Extracellular K Accumulation and "Short QT Syndrome" in Acute Myocardial Ischemia
Y1  - 2007
VL  - 20
IS  - 5
SP  - 417
EP  - 428
AB  - The most profound abnormalities during acute myocardial ischemia are extracellular K(+) accumulation ([K(+)](o)- upward arrow) and shortening of action potential duration or QT interval (APD- downward arrow or QT- downward arrow), which are pivotal in the genesis of ischemic arrhythmias and sudden cardiac death. The ionic mechanisms however remained obscured. We performed studies in a rabbit model of acute global myocardial ischemia in order to explore ionic and metabolic mechanisms for ischemic [K(+)](o)- upward arrow and QT- downward arrow. Exogenous 1-palmitoyl-lysophosphatidylcholine (LPC-16) mimicked the low-perfusion ischemia to produce significant [K(+)](o)- upward arrow and QT- downward arrow. The [K(+)](o)- upward arrow and QT- downward arrow induced by either LPC-16 or ischemia were prevented by dofetilide, a blocker of rapid delayed rectifier K(+) current (I(Kr)), but not by blockers for other K(+) channels. Consistently, dofetilide efficiently abolished the ventricular tachy-arrhythmias induced by ischemia or LPC-16. LPC-16 remarkably shortened APD and enhanced the function of I(Kr) and HERG (the pore-forming subunit of I(Kr)). The effects of LPC-16 manifested with shorter APD (faster repolarization rate) and at more negative potential (membrane repolarization). Dofetilide abolished the I(Kr)/HERG enhancing and APD shortening effects of LPC-16. Our results suggest that LPC-16 accumulation/HERG enhancement may be a link between metabolic trigger and ionic pathway for ischemic [K(+)](o)- upward arrow and QTc- downward arrow. This represents the first documentation of I(Kr)/HERG as the ionic mechanism in ischemic [K(+)](o)- upward arrow and QTc- downward arrow. Inhibition of LPC-16 production and accumulation and/or of I(Kr)/HERG may be a promising therapeutic strategy to attenuate the incidence of lethal arrhythmias associated with ischemic heart disease. Copyright (c) 2007 S. Karger AG, Basel.
N1  - PUBM: Print; JID: 9113221; 2007/04/24 [accepted]; ppublish
CY  - Switzerland
A3  - Anonymous
SN  - 1015-8987
AD  - Department of Pharmacology (State and Provincial Key Laboratory of China), Harbin Medical University, Harbin, Heilongjiang, China.
JF  - Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
JA  - Cell.Physiol.Biochem.
M1  - Journal
ER  - 

TY  - JOUR
ID  - 6371
A1  - Bourbon,M.
A1  - Alves,A. C.
A1  - Medeiros,A. M.
A1  - Silva,S.
A1  - Soutar,A. K.
A1  - on behalf of the investigators of the Portuguese FH study
T1  - Familial hypercholesterolaemia in Portugal
Y1  - 2007
Y2  - Aug 30
AB  - Familial hypercholesterolaemia (FH) is characterised clinically by an increased level of circulating LDL cholesterol that leads to lipid accumulation in tendons and arteries, premature atherosclerosis and increased risk of coronary heart disease (CHD). Although Portugal should have about 20,000 cases, this disease is severely under-diagnosed in our country, this being the first presentation of Portuguese data on FH. A total of 602 blood samples were collected from 184 index patients and 418 relatives from several centres throughout Portugal. Fifty-three different mutations were found in 83 index patients, 79 heterozygous and 4 with two defective LDLR alleles. Additionally, 4 putative alterations were found in 8 patients but were not considered mutations causing disease, mainly because they did not co-segregate with hypercholesterolaemia in the families. Three unrelated patients were found to be heterozygous for the APOB(3500) mutation and two unrelated patients were found to be heterozygous for a novel mutation in PCSK9, predicted to cause a single amino acid substitution, D374H. Cascade screening increased the number of FH patients identified genetically to 204. The newly identified FH patients are now receiving counselling and treatment based on the genetic diagnosis. The early identification of FH patients can increase their life expectancy and quality of life by preventing the development of premature CHD if patients receive appropriate pharmacological treatment.
N1  - PUBM: Print-Electronic; DEP: 20070830; JID: 0242543; 2007/04/16 [received]; 2007/06/19 [revised]; 2007/07/11 [accepted]; aheadofprint
A3  - Anonymous
SN  - 0021-9150
AD  - Unid. Investigacao Cardiovascular, Inst. Nacional de Saude, Lisbon, Portugal; MRC Lipoprotein Group, Clinical Sciences Centre, Hammersmith Hospital, London, UK.
JF  - Atherosclerosis
JA  - Atherosclerosis
M1  - Journal
ER  - 

TY  - JOUR
ID  - 6382
A1  - Bouzas-Mosquera,A.
A1  - Rueda,F.
A1  - Aldama,G.
A1  - Medrano,C.
A1  - Portela,F.
A1  - Zavanella,C.
A1  - Castro-Beiras,A.
T1  - Perventricular pulmonary valvuloplasty under echocardiographic guidance
Y1  - 2007
Y2  - Aug 29
AB  - We report the case of a small neonate with a complex congenital heart disease who successfully underwent a perventricular pulmonary valvuloplasty during the early postoperative period, using echocardiographic guidance alone without fluoroscopy. We describe the technique and the advantages of this novel procedure.
N1  - PUBM: Print-Electronic; DEP: 20070829; JID: 8200291; 2007/04/05 [received]; 2007/06/23 [accepted]; aheadofprint
A3  - Anonymous
SN  - 1874-1754
AD  - Department of Cardiology, Juan Canalejo Hospital, A Coruna, Spain.
JF  - International journal of cardiology
JA  - Int.J.Cardiol.
M1  - Journal
ER  - 

TY  - JOUR
ID  - 6384
A1  - Capel,I.
A1  - Subirana,M. T.
A1  - Rodriguez-Espinosa,J.
A1  - Corcoy,R.
T1  - Hypernatremia in a patient with cyanotic congenital heart disease
Y1  - 2007
Y2  - Aug 29
N1  - PUBM: Print-Electronic; DEP: 20070829; JID: 8200291; 2007/01/25 [received]; 2007/04/23 [accepted]; aheadofprint
A3  - Anonymous
SN  - 1874-1754
AD  - Department of Endocrinology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
JF  - International journal of cardiology
JA  - Int.J.Cardiol.
M1  - Journal
ER  - 

TY  - JOUR
ID  - 6409
A1  - Carney,R. M.
A1  - Freedland,K. E.
T1  - Depression and coronary heart disease: more pieces of the puzzle
Y1  - 2007
Y2  - Sep
VL  - 164
IS  - 9
SP  - 1307
EP  - 1309
N1  - PUBM: Print; JID: 0370512; ppublish
CY  - United States
A3  - Anonymous
SN  - 0002-953X
AD  - Behavioral Medicine Center, 4625 Lindell Blvd., Suite 420, St. Louis, MO 63108. carneyr@bmc.wustl.edu.
JF  - The American Journal of Psychiatry
JA  - Am.J.Psychiatry
M1  - Journal
ER  - 

TY  - JOUR
ID  - 6366
A1  - Chirkov,Y. Y.
A1  - Horowitz,J. D.
T1  - Impaired tissue responsiveness to organic nitrates and nitric oxide: A new therapeutic frontier?
Y1  - 2007
Y2  - Jul 24
AB  - Nitric oxide (NO) is a physiologically important modulator of both vasomotor tone and platelet aggregability. These effects of NO are predominantly mediated by cyclic guanosine-3,'5'-monophosphate (cGMP) via activation of soluble guanylate cyclase. However, in patients with ischemic heart disease, platelets and coronary/peripheral arteries are hyporesponsive to the antiaggregatory and vasodilator effects of NO donors. NO resistance is also associated with a number of coronary risk factors and presents in different disease states. It correlates with conventional measures of "endothelial dysfunction," and represents a multifaceted disorder, in which smooth muscle and platelet NO resistance are equally important, as sites of abnormal NO-driven physiology. NO resistance results largely from a combination of "scavenging" of NO by superoxide anion radical (O(2)(-)) and of (reversible) inactivation of soluble guanylate cyclase. It constitutes an impaired physiological response to endogenous NO (endothelium-derived relaxing factor, EDRF) and, as such, may contribute to the increased risk of ischemic events. Impairment in responsiveness to NO in ischemic patients implies a potential problem that those patients, in greatest need of nitrate therapy, may be least likely to respond. The prognostic impact of NO resistance at vascular and platelet levels has been demonstrated in patients with ischemic heart disease, and it has been shown that a number of agents (angiotensin-converting enzyme [ACE] inhibitors, perhexiline, insulin, and possibly statins) ameliorate this anomaly. The current review examines different aspects of the "NO resistance" phenomenon and discusses some related methodological issues.
N1  - PUBM: Print-Electronic; DEP: 20070724; JID: 7905840; 2007/06/26 [received]; 2007/06/27 [accepted]; aheadofprint
A3  - Anonymous
SN  - 0163-7258
AD  - Cardiology Unit, The Queen Elizabeth Hospital, The University of Adelaide, S.A., Australia.
JF  - Pharmacology & therapeutics
JA  - Pharmacol.Ther.
M1  - Journal
ER  - 

TY  - JOUR
ID  - 6369
A1  - Clark,J. E.
A1  - Sarafraz,N.
A1  - Marber,M. S.
T1  - Potential of p38-MAPK inhibitors in the treatment of ischaemic heart disease
Y1  - 2007
Y2  - Jul 24
AB  - Chronic heart failure is debilitating, often fatal, expensive to treat and common. In most patients it is a late consequence of myocardial infarction (MI). The intracellular signals following infarction that lead to diminished contractility, apoptosis, fibrosis and ultimately heart failure are not fully understood but probably involve p38-mitogen activated protein kinases (p38), a family of serine/threonine kinases which, when activated, cause cardiomyocyte contractile dysfunction and death. Pharmacological inhibitors of p38 suppress inflammation and are undergoing clinical trials in rheumatoid arthritis, Chrohn's disease, psoriasis and surgery-induced tissue injury. In this review, we discuss the mechanisms, circumstances and consequences of p38 activation in the heart. The purpose is to evaluate p38 inhibition as a potential therapy for ischaemic heart disease.
N1  - PUBM: Print-Electronic; DEP: 20070724; JID: 7905840; 2007/06/14 [received]; 2007/06/14 [accepted]; aheadofprint
A3  - Anonymous
SN  - 0163-7258
AD  - The Cardiovascular Division, King's College London, The Rayne Institute, St Thomas' Hospital, London, SE1 7EH, United Kingdom.
JF  - Pharmacology & therapeutics
JA  - Pharmacol.Ther.
M1  - Journal
ER  - 

TY  - JOUR
ID  - 6399
A1  - Colivicchi,F.
A1  - Bassi,A.
A1  - Santini,M.
A1  - Caltagirone,C.
T1  - Discontinuation of Statin Therapy and Clinical Outcome After Ischemic Stroke
Y1  - 2007
Y2  - Aug 30
AB  - BACKGROUND AND PURPOSE: The majority of patients with previous ischemic stroke are expected to benefit significantly from long-term statin therapy. However, discontinuation of medication therapy frequently occurs in clinical practice. The aim of this study was to assess the impact of discontinued statin therapy on clinical outcome in patients discharged after an acute ischemic stroke. METHODS: The study population included 631 consecutive stroke survivors (322 men and 309 women; mean+/-SD age, 70.2+/-7.6 years) without clinical evidence of coronary heart disease. All patients were discharged on statin therapy and were followed up for 12 months after the acute ischemic stroke. RESULTS: Within 12 months from discharge, 246 patients (38.9%) discontinued statin therapy; the mean time from discharge to statin discontinuation was 48.6+/-54.9 days (median time, 30 days; interquartile range, 18 to 55 days). During follow-up, 116 patients died (1-year probability of death=0.18; 95% CI, 0.15 to 0.21). Multivariate analysis demonstrated that after adjustment for all confounders and interactions, statin therapy discontinuation (hazard ratio=2.78; 95% CI, 1.96 to 3.72; P=0.003) was an independent predictor of all-cause 1-year mortality. CONCLUSIONS: A large number of patients discontinue their use of statins early after acute stroke. Moreover, patients discontinuing statins have a significantly increased mortality during the first year after the acute cerebrovascular event. These findings suggest that patient care should be improved during the transition from a hospital setting to outpatient primary care.
N1  - PUBM: Print-Electronic; DEP: 20070830; JID: 0235266; aheadofprint
A3  - Anonymous
SN  - 1524-4628
AD  - From the Cardiovascular Department.
JF  - Stroke; a journal of cerebral circulation
JA  - Stroke
M1  - Journal
ER  - 

TY  - JOUR
ID  - 6383
A1  - Collins,P.
T1  - HDL-C in post-menopausal women: An important therapeutic target
Y1  - 2007
Y2  - Aug 29
AB  - Coronary heart disease is a major cause of mortality in women in Western industrialised countries, particularly after the age of 50 years, coinciding with the onset of the menopause and potentially adverse metabolic changes that occur during the transitional peri-menopausal and post-menopausal periods. Dyslipidaemia characterised by increases in plasma levels of low-density lipoprotein cholesterol (LDL-C), triglycerides and lipoprotein(a) and a decrease in high-density lipoprotein cholesterol (HDL-C) together with the emergence of other diagnostic features of the metabolic syndrome are key factors that increase cardiovascular risk. Treatment beyond LDL-C with a combination of different lipid-modifying therapies may therefore be of greater importance in women than men. Fibrates and nicotinic acid are two treatments that may be added to primary statin therapy. Fibrates are more effective in lowering elevated triglycerides, whereas nicotinic acid is more effective in raising HDL-C. Although there is clearly a need for clinical trials in women, the available data suggests that combination lipid-modifying therapy is a logical treatment strategy in this high-risk patient group.
N1  - PUBM: Print-Electronic; DEP: 20070829; JID: 8200291; 2006/11/27 [received]; 2007/05/16 [revised]; 2007/06/30 [accepted]; aheadofprint
A3  - Anonymous
SN  - 1874-1754
AD  - Department of Cardiac Medicine, National Heart and Lung Institute, Faculty of Medicine, Imperial Colllege London, Technology and Medicine, Dovehouse Street, London, SW3 6LY, UK.
JF  - International journal of cardiology
JA  - Int.J.Cardiol.
M1  - Journal
ER  - 

TY  - JOUR
ID  - 6317
A1  - Costello,Barbara
T1  - Using Blackboard in Library Instruction: Addressing the Learning Styles of Generations X and Y
Y1  - 2004
Y2  - November
VL  - 30
IS  - 6
SP  - 452
EP  - 460
KW  - Internet -- Florida
KW  - Cognitive style
KW  - Cognition
KW  - Computer-assisted instruction
KW  - Bibliographic instruction -- College and university students
KW  - Blackboard (Web site)
KW  - Internet -- College and university libraries
KW  - Echo boom generation
KW  - Libraries, College -- Instruction in use -- Computer aids
KW  - Generation X
N1  - Additional Info: US; R; Date of Entry: 20041230
A3  - Anonymous
SN  - 0099-1333
AV  - FirstSearch indicates your institution subscribes to this publication. Libraries worldwide that own item: 1549 University of Michigan Library Search the Mirlyn catalog at the University of Michigan
JF  - Journal of Academic Librarianship
JA  - J.Acad.Libr.
M1  - Journal
ER  - 

TY  - VIDEO
ID  - 6352
A1  - Cuarâon,Alfonso
A1  - Columbus,Chris
A1  - Heyman,David
A1  - Radcliffe,Mark
A1  - Kloves,Steven
A1  - Radcliffe,Daniel
A1  - Watson,Emma
A1  - Grint,Rupert
A1  - Coltrane,Robbie
A1  - Rickman,Alan
A1  - Seresin,Michael
A1  - Williams,John
A1  - Rowling,J. K.
A1  - Warner Bros
A1  - Warner Home Video
A1  - Heyday Films
A1  - 1492 Pictures
T1  - Harry Potter and the prisoner of Azkaban
Y1  - 2004
KW  - Potter, Harry (Fictitious character)
KW  - Drama
KW  - Hogwarts School of Witchcraft and Wizardry (Imaginary place)
KW  - Wizards England
KW  - Witches England
KW  - Escapes
KW  - Magic England
KW  - Video recordings for the hearing impaired
KW  - Rowling, J. K
KW  - Film and video adaptations
N1  - 085392844524; 28445; 28445.2.A (disc 2); [videorecording] / Warner Bros ; 1492 Pictures ; Heyday Films ; producers, Chris Columbus, David Heyman, Mark Radcliffe ; screenplay, Steve Kloves ; directed by Alfonso Cuarâon.; 2 videodiscs (ca. 142 min.) : sd., col. ; 4 3/4 in. + 1 booklet; DVD; Dolby Digital 5.1 surround.; Daniel Radcliffe, Emma Watson, Rupert Grint, Robbie Coltrane, Alan Rickman, Maggie Smith, Michael Gambon, David Thewlis, Gary Oldman.; Director of photography, Michael Seresin ; editor, Steven Weisberg ; music, John Williams ; costume designer, Jany Temime ; production designer, Stuart Craig ; visual effects supervisors, Tim Burke, Roger Guyett.; Based on the novel by J.K. Rowling.; Originally released as a motion picture in 2004.; Special features (disc 2): a selection of exclusive never-before-seen footage ; "Creating the vision" an interview with J.K. Rowling and the filmmakers ; three interactive challenges ; self-guided iPIX tours ; interviews with cast lead Johnny Vaughn and the Shrunken Head ; meet the animal trainer ; "Choir practice" sing-along with Hogwarts choir ; Hogwarts portrait gallery ; conjuring a scene ; theatrical trailers from all three Harry Potter films ; Electronic Arts game preview ; DVD-ROM features: Wizard trading cards ; Hogwarts timeline.
VL  - 2-disc widescreen
PB  - Warner Home Video
CY  - Burbank, Calif.
A3  - Anonymous
SN  - 0790783517
M1  - Video/DVD
ER  - 

TY  - JOUR
ID  - 6318
A1  - Dalrymple,Connie
T1  - Perceptions and practices of learning styles in library instruction
Y1  - 2002
Y2  - May
VL  - 63
IS  - 3
SP  - 261
EP  - 273
KW  - Libraries -- Instruction in use
KW  - Cognitive style
AB  - Learning style theory has gained a broad base of acceptance in the library field. Less clear is how well librarians have assimilated learning style theory and how consciously they are incorporating its tenets into their day-to-day teaching. This survey was conducted to ascertain how instruction librarians and other library professionals learn, assimilate, and utilize learning style theory. Results show that the majority of librarians are aware of learning style theory, but many are unsure of its validity or proper application in library settings. Recommendations include increased coverage of instructional theory in library schools and more rigorous scientific studies of learning style--sensitive practice in library instruction settings. Reprinted by permission of the publisher.
N1  - Additional Info: United States; Details: bibl f graph tab.; Peer-reviewed journal; Date of Entry: 20020717
A3  - Anonymous
SN  - 0010-0870
AV  - FirstSearch indicates your institution subscribes to this publication. Libraries worldwide that own item: 2323 University of Michigan Library Search the Mirlyn catalog at the University of Michigan
JF  - College & Research Libraries
JA  - Coll.Res.Libr.
M1  - Journal
ER  - 

TY  - JOUR
ID  - 6379
A1  - Diehm,N.
A1  - Benenati,J. F.
A1  - Becker,G. J.
A1  - Quesada,R.
A1  - Tsoukas,A. I.
A1  - Katzen,B. T.
A1  - Kovacs,M.
T1  - Anemia is associated with abdominal aortic aneurysm (AAA) size and decreased long-term survival after endovascular AAA repair
Y1  - 2007
Y2  - Aug 29
AB  - OBJECTIVE: Anemia is a common comorbid condition in various inflammatory states and an established predictor of mortality in patients with chronic heart failure, ischemic heart disease, and end-stage renal disease. The present study of patients with abdominal aortic aneurysm (AAA) undergoing endovascular repair (EVAR) assessed the relationships between baseline hemoglobin concentration and AAA size, as well as anemia and long-term survival. METHODS: Between March 1994 and November 2006, 711 patients (65 women, mean age 75.8 +/- 7.8 years) underwent elective EVAR. Anemia was defined as a hemoglobin level <13 g/dL in men and <12 g/dL in women. Post-EVAR mean follow-up was 48.3 +/- 32.0 months. Association of hemoglobin level with AAA size was assessed with multiple linear regression. Mortality was determined with use of the internet-based Social Security Death Index and the electronic hospital record. Kaplan-Meier survival curves of anemic and nonanemic patient groups were compared by the log-rank method. Multivariable logistic regression models were used to determine the influence of anemia on vital status after EVAR. RESULTS: A total of 218/711 (30.7%) of AAA patients undergoing EVAR had anemia at baseline. After adjustment for various risk factors, hemoglobin level was inversely related to maximum AAA diameter (beta: - .144, 95%-CI: -1.482 - .322, P = .002). Post-EVAR survival was 65.5% at 5 years and 44.4% at 10 years. In long-term follow-up, survival was significantly lower in patients with anemia as compared to patients without anemia (P < .0001 by log-rank). Baseline hemoglobin levels were independently related to long-term mortality in multivariable Cox regression analysis adjusted for various risk factors (adjusted HR: 0.866, 95% CI: .783 to .958, P = .005). Within this model, statin use (adjusted HR: .517, 95% CI: .308 to .868, P = .013) was independently related to long-term survival, whereas baseline AAA diameter (adjusted HR: 1.022, 95% CI: 1.009 to 1.036, P = .001) was an independently associated with increased mortality. CONCLUSIONS: Baseline hemoglobin concentration is independently associated with AAA size and reduced long-term survival following EVAR. Thus, the presence or absence of anemia offers a potential refinement of existing risk stratification instruments.
N1  - PUBM: Print-Electronic; DEP: 20070829; JID: 8407742; 2007/04/24 [received]; 2007/06/10 [accepted]; aheadofprint
A3  - Anonymous
SN  - 0741-5214
AD  - Department of Baptist Cardiac and Vascular Institute, Division of Interventional Radiology, Miami, 8900 North Kendall Drive, Miami, Florida, USA; Department of Swiss Cardiovascular Center, Division of Clinical and Interventional Angiology and Va(TRUNCATED)
JF  - Journal of vascular surgery : official publication, the Society for Vascular Surgery [and] International Society for Cardiovascular Surgery, North American Chapter
JA  - J.Vasc.Surg.
M1  - Journal
ER  - 

TY  - JOUR
ID  - 6398
A1  - Dumont,J.
A1  - Zureik,M.
A1  - Bauters,C.
A1  - Grupposo,M. C.
A1  - Cottel,D.
A1  - Montaye,M.
A1  - Hamon,M.
A1  - Ducimetiere,P.
A1  - Amouyel,P.
A1  - Brousseau,T.
T1  - Association of OAZ1 Gene Polymorphisms With Subclinical and Clinical Vascular Events
Y1  - 2007
Y2  - Aug 30
AB  - OBJECTIVE: Proliferation and migration of vascular smooth muscle cells (VSMCs) are striking features shared by vascular ageing, atherosclerosis, and in-stent restenosis. VSMC biology depends in part on polyamines whose metabolism is closely regulated by ornithine decarboxylase antizyme 1 (OAZ1). Therefore, we sought for association between OAZ1 gene polymorphisms and various outcomes involving VSMC proliferation. METHODS AND RESULTS: Systematic screening of the OAZ1 gene enabled to detect 21 variants. The impact of 4 selected tag polymorphisms (+849C/T, +851G/T, +1804G/A, and +2222A/G) was evaluated in 3 independent association studies. In a sample of 205 patients, the +2222G allele was associated with an increased risk of 6-month coronary in-stent restenosis (OR [95%CI]=2.1 [1.2 to 3.6]; P=0.0071). In a sample of 1001 subjects participating to the EVA study, the +2222G allele was longitudinally associated with a 4-year increase in common carotid intima-media thickness (P=0.047). In a case-control study (466 cases versus 466 controls), the risk of coronary heart disease associated with the +2222G allele was 1.3 (95%CI=[1.1 to 1.6]; P=0.026). No other significant association was consistently detected. CONCLUSIONS: We identified the OAZ1+2222A/G polymorphism as a potential genetic marker of vascular events. Our findings strengthen the hypothesis that the polyamine metabolism plays a role in vascular diseases.
N1  - PUBM: Print-Electronic; DEP: 20070830; JID: 9505803; aheadofprint
A3  - Anonymous
SN  - 1524-4636
AD  - Inserm, U744, Lille; Institut Pasteur de Lille, Lille; Universite de Lille 2, UMR-S744, Lille; Inserm, U780, Villejuif; Paris-Sud, UMR-S780; CHRU de Lille, Lille; CHU de Caen, Caen, France.
JF  - Arteriosclerosis, Thrombosis, and Vascular Biology
JA  - Arterioscler.Thromb.Vasc.Biol.
M1  - Journal
ER  - 

TY  - JOUR
ID  - 6319
A1  - Felder,R. M.
A1  - Silverman,L. K.
T1  - Learning and Teaching Styles in Engineering Education
Y1  - 1988
VL  - 78
IS  - 7
SP  - 674
EP  - 681
A3  - Anonymous
JF  - Engineering Education
M1  - Journal
ER  - 

TY  - JOUR
ID  - 6410
A1  - Hall,R.
A1  - Saukko,P. M.
A1  - Evans,P. H.
A1  - Qureshi,N.
A1  - Humphries,S. E.
T1  - Assessing family history of heart disease in primary care consultations: a qualitative study
Y1  - 2007
Y2  - Aug 28
AB  - BACKGROUND: Current primary prevention guidelines recommend the assessment of family history of coronary heart disease (CHD) to identify at-risk individuals. OBJECTIVE: To examine how clinicians and patients understand and communicate family history in the context of CHD risk assessment in primary care. METHODS: A qualitative study. Patients completed a validated family history questionnaire. Consultations with clinicians were video recorded, and semi-structured interviews conducted with patients after consultation. The participants were 21 primary care patients and seven primary care clinicians (two practice nurses, five GPs). Four practices in South West England. RESULTS: Patients and clinicians usually agreed about the patient's level of risk and how to reduce it. Patients were mostly satisfied with their consultations and having their family history assessed. However, three issues were identified from the consultations which contributed to concerns and unanswered questions for patients. Problems arose when there were few modifiable risk factors to address. Firstly, patients' explanations of their family history were not explored in the consultation. Secondly, the relationship between the patient's family history and their other risk factors, such as smoking or cholesterol, was rarely discussed. Thirdly, clinicians did not explain the integration of family history into the patient's overall cardiovascular disease risk. CONCLUSIONS: Clinicians appeared to lack a rhetoric to discuss family history, in terms of capturing both genetic and environmental factors and its relation to other risk factors. This created uncertainties for patients and carries potential clinical and social implications. There is a need for better guidance for primary care clinicians about family history assessment.
N1  - PUBM: Print-Electronic; DEP: 20070828; JID: 8500875; aheadofprint
A3  - Anonymous
SN  - 0263-2136
AD  - ESRC Centre for Genomics in Society, Byrne House, St German's Road, University of Exeter, Exeter EX4 4PJ.
JF  - Family practice
JA  - Fam.Pract.
M1  - Journal
ER  - 

TY  - JOUR
ID  - 6370
A1  - Hernesniemi,J. A.
A1  - Karhunen,P. J.
A1  - Rontu,R.
A1  - Ilveskoski,E.
A1  - Kajander,O.
A1  - Goebeler,S.
A1  - Viiri,L. E.
A1  - Pessi,T.
A1  - Hurme,M.
A1  - Lehtimaki,T.
T1  - Interleukin-18 promoter polymorphism associates with the occurrence of sudden cardiac death among Caucasian males: The Helsinki Sudden Death Study
Y1  - 2007
Y2  - Aug 30
AB  - OBJECTIVE: The increased plasma concentrations of pro-atherogenic and cardiomyocyte hypertrophic cytokine interleukin 18 (IL-18) predict mortality in patients with coronary heart disease (CHD) in addition to predicting the outcome of heart failure. The IL-18 gene has a functional -137G/C polymorphism (rs187238) in the promoter region. The C allele carriage is associated with attenuated IL-18 production. The effect of IL-18 genotype on SCD is unknown. We studied the association of the IL-18 gene -137G/C polymorphism with the occurrence of sudden cardiac death (SCD). METHODS: Using the TaqMan 5' nuclease assay, we genotyped two independent consecutive and prospective autopsy series which were included in the Helsinki Sudden Death Study. RESULTS: Of the 663 men, 359 (54.1%) had the wild-type GG-genotype, 261 (39.4%) were heterozygotes (CG) and 43 (6.5%) were CC homozygotes. Compared to the GG homozygotes, the C allele carriers (i.e. subjects having CC or CG genotypes) had a lower adjusted risk for SCD from any cause (odds ratio [OR] 0.49; 95% confidence interval [CI], 0.31-0.77, p=0.002), for SCD due to CHD (OR 0.51; 95% CI, 0.32-0.82, p=0.005), and for SCD caused by non-coronary heart diseases (OR 0.34; 95% CI 0.13-0.90, p=0.030). CONCLUSION: IL-18 promoter -137G/C polymorphism, which regulates the expression of IL-18, is an important predictor of SCD from any cause as well as SCD in patients with and without underlying CHD.
N1  - PUBM: Print-Electronic; DEP: 20070830; JID: 0242543; 2007/04/17 [received]; 2007/07/04 [revised]; 2007/07/11 [accepted]; aheadofprint
A3  - Anonymous
SN  - 0021-9150
AD  - Laboratory of Atherosclerosis Genetics, Tampere University Hospital and the Department of Clinical Chemistry, Medical School, University of Tampere, Tampere, Finland.
JF  - Atherosclerosis
JA  - Atherosclerosis
M1  - Journal
ER  - 

TY  - VIDEO
ID  - 6321
A1  - Heyman,David
A1  - Kloves,Steven
A1  - Columbus,Chris
A1  - Radcliffe,Daniel
A1  - Grint,Rupert
A1  - Watson,Emma
A1  - Cleese,John
A1  - Coltrane,Robbie
A1  - Griffiths,Richard
A1  - Harris,Richard
A1  - Smith,Maggie
A1  - Rickman,Alan
A1  - Williams,John
A1  - Rowling,J. K.
A1  - Warner Bros
A1  - Heyday Films
A1  - 1492 Pictures
A1  - Warner Home Video
T1  - Harry Potter and the sorcerer's stone
Y1  - 2002
Y2  - 2001
KW  - Potter, Harry (Fictitious character)
KW  - Drama
KW  - Wizards England
KW  - Magic England
KW  - Hogwarts School of Witchcraft and Wizardry (Imaginary place)
KW  - Schools England
KW  - Fantasy films
KW  - Video recordings for the hearing impaired
AB  - Rescued from the outrageous neglect of his aunt and uncle, a young boy with a great destiny proves his worth while attending Hogwarts School for Wizards and Witches.
N1  - 22467; [videorecording] / Warner Bros. presents a Heyday Films/1492 Pictures/Duncan Henderson production ; produced by David Heyman ; screenplay by Steven Kloves ; directed by Chris Columbus.; 2 videodiscs (152 min.) : sd., col. ; 4 3/4 in; DVD; Dolby digital 5.1 surround; Region 1; DVD-ROM features require Windows 95 or higher, DVD-ROM drive, Internet access and Internet browser.; Daniel Radcliffe, Rupert Grint, Emma Watson, John Cleese, Robbie Coltrane, Warwick Davis, Richard Griffiths, Richard Harris, Ian Hart, John Hurt, Alan Rickman, Fiona Shaw, Maggie Smith, Julie Walters.; Director of photography, John Seale; editor, Richard Francis-Bruce; music, John Williams; production design, Stuart Craig; costume design, Judianna Makovsky.; Originally produced as a motion picture in 2001.; Based on the novel by J.K. Rowling.; Widescreen (2.35:1 aspect ratio).; MPAA rating: PG.; Special features: Never-before-seen footage; 3600 self-guided tour of Hogwarts; interview with director, Chris Columbus, and producer, David Heyman; learn how to play quidditch; meet the ghosts of Hogwarts; cast a spell over a scene, mix potions, perform transfigurations, sneak past Fluffy, explore Diagon Alley, have a wand choose you, catch a snitch; DVD-ROM features: colect wizard trading cards; be sorted by the Sorting Hat; download screensaver and Remembrall; receive owl emails; Internet links.
VL  - Special Widescreen
PB  - Warner Home Video
CY  - Burbank, CA
A3  - Anonymous
SN  - 079076735X
M1  - Video/DVD
ER  - 

TY  - VIDEO
ID  - 6336
A1  - Heyman,David
A1  - Kloves,Steven
A1  - Columbus,Chris
A1  - Radcliffe,Daniel
A1  - Grint,Rupert
A1  - Watson,Emma
A1  - Cleese,John
A1  - Coltrane,Robbie
A1  - Griffiths,Richard
A1  - Harris,Richard
A1  - Smith,Maggie
A1  - Rickman,Alan
A1  - Williams,John
A1  - Rowling,J. K.
A1  - Warner Bros
A1  - Heyday Films
A1  - 1492 Pictures
A1  - Warner Home Video
T1  - Harry Potter and the sorcerer's stone
Y1  - 2002
Y2  - 2001
KW  - Potter, Harry (Fictitious character)
KW  - Drama
KW  - Wizards England
KW  - Magic England
KW  - Hogwarts School of Witchcraft and Wizardry (Imaginary place)
KW  - Schools England
KW  - Fantasy films
KW  - Video recordings for the hearing impaired
AB  - Rescued from the outrageous neglect of his aunt and uncle, a young boy with a great destiny proves his worth while attending Hogwarts School for Wizards and Witches.
N1  - 22467; [videorecording] / Warner Bros. presents a Heyday Films/1492 Pictures/Duncan Henderson production ; produced by David Heyman ; screenplay by Steven Kloves ; directed by Chris Columbus.; 2 videodiscs (152 min.) : sd., col. ; 4 3/4 in; DVD; Dolby digital 5.1 surround; Region 1; DVD-ROM features require Windows 95 or higher, DVD-ROM drive, Internet access and Internet browser.; Daniel Radcliffe, Rupert Grint, Emma Watson, John Cleese, Robbie Coltrane, Warwick Davis, Richard Griffiths, Richard Harris, Ian Hart, John Hurt, Alan Rickman, Fiona Shaw, Maggie Smith, Julie Walters.; Director of photography, John Seale; editor, Richard Francis-Bruce; music, John Williams; production design, Stuart Craig; costume design, Judianna Makovsky.; Originally produced as a motion picture in 2001.; Based on the novel by J.K. Rowling.; Widescreen (2.35:1 aspect ratio).; MPAA rating: PG.; Special features: Never-before-seen footage; 3600 self-guided tour of Hogwarts; interview with director, Chris Columbus, and producer, David Heyman; learn how to play quidditch; meet the ghosts of Hogwarts; cast a spell over a scene, mix potions, perform transfigurations, sneak past Fluffy, explore Diagon Alley, have a wand choose you, catch a snitch; DVD-ROM features: colect wizard trading cards; be sorted by the Sorting Hat; download screensaver and Remembrall; receive owl emails; Internet links.
VL  - Special Widescreen
PB  - Warner Home Video
CY  - Burbank, CA
A3  - Anonymous
SN  - 079076735X
M1  - Video/DVD
ER  - 

TY  - VIDEO
ID  - 6350
A1  - Heyman,David
A1  - Kloves,Steven
A1  - Columbus,Chris
A1  - Radcliffe,Daniel
A1  - Grint,Rupert
A1  - Watson,Emma
A1  - Cleese,John
A1  - Coltrane,Robbie
A1  - Griffiths,Richard
A1  - Harris,Richard
A1  - Smith,Maggie
A1  - Rickman,Alan
A1  - Williams,John
A1  - Rowling,J. K.
A1  - Warner Bros
A1  - Heyday Films
A1  - 1492 Pictures
A1  - Warner Home Video
T1  - Harry Potter and the sorcerer's stone
Y1  - 2002
Y2  - 2001
KW  - Potter, Harry (Fictitious character)
KW  - Drama
KW  - Wizards England
KW  - Magic England
KW  - Hogwarts School of Witchcraft and Wizardry (Imaginary place)
KW  - Schools England
KW  - Fantasy films
KW  - Video recordings for the hearing impaired
AB  - Rescued from the outrageous neglect of his aunt and uncle, a young boy with a great destiny proves his worth while attending Hogwarts School for Wizards and Witches.
N1  - 085392133123; 21331; [videorecording] / Warner Bros. presents a Heyday Films/1492 Pictures/Duncan Henderson production ; produced by David Heyman ; screenplay by Steven Kloves ; directed by Chris Columbus.; 2 videodiscs (DVD) (152 min.) : sd., col. ; 4 3/4 in; DVD; Dolby digital 5.1 surround; Region 1; DVD-ROM features require Windows 95 or higher, DVD-ROM drive, Internet access and Internet browser.; Daniel Radcliffe, Rupert Grint, Emma Watson, John Cleese, Robbie Coltrane, Warwick Davis, Richard Griffiths, Richard Harris, Ian Hart, John Hurt, Alan Rickman, Fiona Shaw, Maggie Smith, Julie Walters.; Director of photography, John Seale; editor, Richard Francis-Bruce; music, John Williams; production design, Stuart Craig; costume design, Judianna Makovsky.; Originally produced as a motion picture in 2001.; Based on the novel by J.K. Rowling.; MPAA rating: PG.; Special features: Never-before-seen footage; 3600 self-guided tour of Hogwarts; interview with director, Chris Columbus, and producer, David Heyman; learn how to play quidditch; meet the ghosts of Hogwarts; cast a spell over a scene, mix potions, perform transfigurations, sneak past Fluffy, explore Diagon Alley, have a wand choose you, catch a snitch; DVD-ROM features: colect wizard trading cards; be sorted by the Sorting Hat; download screensaver and Remembrall; receive owl emails; Internet links.
VL  - Standard version
PB  - Warner Home Video
CY  - Burbank, CA
A3  - Anonymous
SN  - 0790767341
M1  - Video/DVD
ER  - 

TY  - VIDEO
ID  - 6320
A1  - Heyman,David
A1  - Kloves,Steven
A1  - Columbus,Chris
A1  - Radcliffe,Daniel
A1  - Watson,Emma
A1  - Grint,Rupert
A1  - Branagh,Kenneth
A1  - Cleese,John
A1  - Coltrane,Robbie
A1  - Davis,Warwick
A1  - Griffiths,Richard
A1  - Harris,Richard
A1  - Isaacs,Jason
A1  - Rickman,Alan
A1  - Shaw,Fiona
A1  - Smith,Maggie
A1  - Rowling,J. K.
A1  - Warner Bros. Pictures
A1  - Heyday Films
A1  - 1492 Pictures
A1  - Warner Home Video
T1  - Harry Potter and the Chamber of Secrets
Y1  - 2003
Y2  - 2002
KW  - Potter, Harry (Fictitious character)
KW  - Drama
KW  - Wizards England
KW  - Magic England
KW  - Hogwarts School of Witchcraft and Wizardry (Imaginary place)
KW  - Video recordings for the hearing impaired
AB  - Finds young wizard Harry and his friends Ron and Hermoine facing new challenges during their second year at Hogwarts School of Witchcraft and Wizardry as they try to uncover a dark force that is terrorizing the school.
N1  - 085392359226; 23592; [videorecording] / Warner Bros. Pictures presents a Heyday Films/1492 Pictures production of a Chris Columbus film ; screenplay by Steve Kloves ; produced by David Heyman ; directed by Chris Columbus.; 2 videodiscs (DVD) (161 min.) : sd., col. ; 4 3/4 in; DVD; Dolby digital 5.1 surround; Region 1; DVDöROM features require Windows 95 or higher and DVD-ROM drive.; Daniel Radcliffe, Emma Watson, Rupert Grint, Kenneth Branagh, John Cleese, Robbie Coltrane, Warwick Davis, Richard Griffiths, Richard Harris, Jason Isaacs, Alan Rickman, Fiona Shaw, Maggie Smith, Julie Walters.; Originally released as a motion picture in 2002.; Based on the novel by J.K. Rowling.; Widescreen (2.35:1 aspect ratio); enhanced for 16 x 9 televisions.; MPAA rating: PG.; Special features: 19 additional/extended scenes; interviews with Daniel Radcliffe (Harry), Rupert Grint (Ron), Emma Watson (Hermione) and other cast members; an exclusive interview with author J.K. Rowling and screenwriter Steve Kloves; self-guided tours allowing viewers to linger on the details of the Chamber of Secrets, including places never shown in the film such as more Diagon Alley shops; activities allow viewers to escape the Forbidden Forest, sneak into the Chamber and more; visit Lockhart's; class and get a closer look at his photos and memorabilia through the use of still galleries; Hogwarts official, animated timeline; 15 special DVD-ROM features including: The One VoiceDVD technology will allow users to navigate through the DVD-ROM features and access set top features using only their voices; an animated, interactive Hogwarts timeline; a slider puzzle challenge; printable magic trading cards; jigsaw puzzles, matching challenges, downloadable screensavers and more.
VL  - Widescreen
PB  - Warner Home Video
CY  - Burbank, CA
A3  - Anonymous
SN  - 0790773104
M1  - Video/DVD
ER  - 

TY  - VIDEO
ID  - 6342
A1  - Heyman,David
A1  - Kloves,Steven
A1  - Columbus,Chris
A1  - Radcliffe,Daniel
A1  - Watson,Emma
A1  - Grint,Rupert
A1  - Branagh,Kenneth
A1  - Cleese,John
A1  - Coltrane,Robbie
A1  - Davis,Warwick
A1  - Griffiths,Richard
A1  - Harris,Richard
A1  - Isaacs,Jason
A1  - Rickman,Alan
A1  - Shaw,Fiona
A1  - Smith,Maggie
A1  - Rowling,J. K.
A1  - Warner Bros. Pictures
A1  - Heyday Films
A1  - 1492 Pictures
A1  - Warner Home Video
T1  - Harry Potter and the Chamber of Secrets
Y1  - 2003
Y2  - 2002
KW  - Potter, Harry (Fictitious character)
KW  - Drama
KW  - Wizards England
KW  - Magic England
KW  - Hogwarts School of Witchcraft and Wizardry (Imaginary place)
KW  - Video recordings for the hearing impaired
AB  - Finds young wizard Harry and his friends Ron and Hermoine facing new challenges during their second year at Hogwarts School of Witchcraft and Wizardry as they try to uncover a dark force that is terrorizing the school.
N1  - 23592; [videorecording] / Warner Bros. Pictures presents a Heyday Films/1492 Pictures production of a Chris Columbus film ; screenplay by Steve Kloves ; produced by David Heyman ; directed by Chris Columbus.; 2 videodiscs (161 min.) : sd., col. ; 4 3/4 in; DVD; Dolby digital 5.1 surround; Region 1; DVDöROM features require Windows 95 or higher and DVD-ROM drive.; Daniel Radcliffe, Emma Watson, Rupert Grint, Kenneth Branagh, John Cleese, Robbie Coltrane, Warwick Davis, Richard Griffiths, Richard Harris, Jason Isaacs, Alan Rickman, Fiona Shaw, Maggie Smith, Julie Walters.; Originally released as a motion picture in 2002.; Based on the novel by J.K. Rowling.; Widescreen (2.35:1 aspect ratio); enhanced for 16 x 9 televisions.; MPAA rating: PG.; Special features: 19 additional/extended scenes; interviews with Daniel Radcliffe (Harry), Rupert Grint (Ron), Emma Watson (Hermione) and other cast members; an exclusive interview with author J.K. Rowling and screenwriter Steve Kloves; self-guided tours allowing viewers to linger on the details of the Chamber of Secrets, including places never shown in the film such as more Diagon Alley shops; activities allow viewers to escape the Forbidden Forest, sneak into the Chamber and more; visit Lockhart's; class and get a closer look at his photos and memorabilia through the use of still galleries; Hogwarts official, animated timeline; 15 special DVD-ROM features including: The One VoiceDVD technology will allow users to navigate through the DVD-ROM features and access set top features using only their voices; an animated, interactive Hogwarts timeline; a slider puzzle challenge; printable magic trading cards; jigsaw puzzles, matching challenges, downloadable screensavers and more.
VL  - Widescreen
PB  - Warner Home Video
CY  - Burbank, CA
A3  - Anonymous
SN  - 0790773104
M1  - Video/DVD
ER  - 

TY  - VIDEO
ID  - 6349
A1  - Heyman,David
A1  - Kloves,Steven
A1  - Columbus,Chris
A1  - Radcliffe,Daniel
A1  - Watson,Emma
A1  - Grint,Rupert
A1  - Branagh,Kenneth
A1  - Cleese,John
A1  - Coltrane,Robbie
A1  - Davis,Warwick
A1  - Griffiths,Richard
A1  - Harris,Richard
A1  - Isaacs,Jason
A1  - Rickman,Alan
A1  - Shaw,Fiona
A1  - Smith,Maggie
A1  - Rowling,J. K.
A1  - Warner Bros. Pictures
A1  - Heyday Films
A1  - 1492 Pictures
A1  - Warner Home Video
T1  - Harry Potter and the Chamber of Secrets
Y1  - 2003
Y2  - 2002
KW  - Potter, Harry (Fictitious character)
KW  - Drama
KW  - Wizards England
KW  - Magic England
KW  - Hogwarts School of Witchcraft and Wizardry (Imaginary place)
KW  - Video recordings for the hearing impaired
AB  - Finds young wizard Harry and his friends Ron and Hermoine facing new challenges during their second year at Hogwarts School of Witchcraft and Wizardry as they try to uncover a dark force that is terrorizing the school.
N1  - 085392359226; 23592; [videorecording] / Warner Bros. Pictures presents a Heyday Films/1492 Pictures production of a Chris Columbus film ; screenplay by Steve Kloves ; produced by David Heyman ; directed by Chris Columbus.; 2 videodiscs (DVD) (161 min.) : sd., col. ; 4 3/4 in; DVD; Dolby digital 5.1 surround; Region 1; DVDöROM features require Windows 95 or higher and DVD-ROM drive.; Daniel Radcliffe, Emma Watson, Rupert Grint, Kenneth Branagh, John Cleese, Robbie Coltrane, Warwick Davis, Richard Griffiths, Richard Harris, Jason Isaacs, Alan Rickman, Fiona Shaw, Maggie Smith, Julie Walters.; Originally released as a motion picture in 2002.; Based on the novel by J.K. Rowling.; Widescreen (2.35:1 aspect ratio); enhanced for 16 x 9 televisions.; MPAA rating: PG.; Special features: 19 additional/extended scenes; interviews with Daniel Radcliffe (Harry), Rupert Grint (Ron), Emma Watson (Hermione) and other cast members; an exclusive interview with author J.K. Rowling and screenwriter Steve Kloves; self-guided tours allowing viewers to linger on the details of the Chamber of Secrets, including places never shown in the film such as more Diagon Alley shops; activities allow viewers to escape the Forbidden Forest, sneak into the Chamber and more; visit Lockhart's; class and get a closer look at his photos and memorabilia through the use of still galleries; Hogwarts official, animated timeline; 15 special DVD-ROM features including: The One VoiceDVD technology will allow users to navigate through the DVD-ROM features and access set top features using only their voices; an animated, interactive Hogwarts timeline; a slider puzzle challenge; printable magic trading cards; jigsaw puzzles, matching challenges, downloadable screensavers and more.
VL  - Widescreen
PB  - Warner Home Video
CY  - Burbank, CA
A3  - Anonymous
SN  - 0790773104
M1  - Video/DVD
ER  - 

TY  - JOUR
ID  - 6386
A1  - Iemura,M.
T1  - New diagnostic methods and modalities for congenital heart disease
Y1  - 2007
Y2  - Jul
VL  - 60
IS  - 8 Suppl
SP  - 667
EP  - 673
AB  - Ultrasound imaging of cardiovascular structures has progressed rapidly from standard surface techniques to real-time 3-dimensional echocardiography and intracardiac echocardiography. Especially, 3-dimensional echocardiography is having a significant impact on the evaluation of congenital heart diseases (CHD). However, the present system of prenatal screening for CHD in Japan is not as efficient as it is in some Western countries. For this reason, the number of patient referrals for fetal echocardiography and the fetal diagnosis of CHD increased year after year. Gestational age at referral and at the diagnosis of CHD has increased rapidly in recent years. To improve the patient's prognosis, we should form more simple prenatal primary screening programs for CHD. In addition, we require the progression of the diagnostic modalities and familiarize these new diagnostic methods and modalities.
N1  - PUBM: Print; JID: 0413533; ppublish
CY  - Japan
A3  - Anonymous
SN  - 0021-5252
AD  - Center for Cardiovascular Disease, Kurume University School of Medicine, Kurume, Japan.
JF  - Kyobu geka.The Japanese journal of thoracic surgery
JA  - Kyobu Geka
M1  - Journal
ER  - 

TY  - JOUR
ID  - 6387
A1  - Ito,H.
T1  - Assessment of coronary heart diseases by echocardiography
Y1  - 2007
Y2  - Jul
VL  - 60
IS  - 8 Suppl
SP  - 653
EP  - 660
AB  - Echocardiography plays an important role in deciding the operative indication in patients with coronary artery diseases. On deciding the indication of coronary artery bypass graft, dobutamine stress echocardiography provides accurate information on presence or absence of myocardial ischemia and of myocardial viability in each coronary artery territory. Assessment of the coronary blood flow velocity using high-frequency Doppler enables us to examine the presence of coronary stenosis and the patency of bypass graft. Left ventricular remodeling is a cause of progressive heart failure after myocardial infarction, and echocardiography allows us to measure the left ventricular volume and ejection fraction. Real-time 3-dimensional echocardiography has made this measurement process accurate and easy. Dyssynchrony is another mechanism that worsens ventricular contractile performance, and several echocardiographic indexes were proposed to diagnose it. Cardiac resynchronization therapy, if it is performed with cardiac surgery, can correct the dyssynchrony and enhance the functional improvement. Severity of diastolic dysfunction can predict the prognosis of patients with coronary artery diseases, and we can assess it from the mitral flow velocity pattern; normal, abnormal, pseudonormal and restrictive. Thus, echocariography provides a potential method to evaluate myocardial viability, myocardial ischemia, and pathophysiology of heart failure.
N1  - PUBM: Print; JID: 0413533; ppublish
CY  - Japan
A3  - Anonymous
SN  - 0021-5252
AD  - Division of Cardiology, Sakurabashi Watanabe Hospital, Osaka, Japan.
JF  - Kyobu geka.The Japanese journal of thoracic surgery
JA  - Kyobu Geka
M1  - Journal
ER  - 

TY  - JOUR
ID  - 6381
A1  - Katz,D. A.
A1  - Aufderheide,T. P.
A1  - Bogner,M.
A1  - Rahko,P. S.
A1  - Hillis,S. L.
A1  - Selker,H. P.
T1  - Do Emergency Department Patients With Possible Acute Coronary Syndrome Have Better Outcomes When Admitted to Cardiology Versus Other Services?
Y1  - 2007
Y2  - Aug 29
AB  - STUDY OBJECTIVE: Emergency physicians need to consider potential differences in quality of care across admitting services in their triage decisions. For emergency department (ED) patients with possible acute coronary syndrome who require hospitalization, there are relatively few data to guide emergency physicians in deciding whether admission to a cardiology service bed yields better outcomes than admission to a noncardiology service. METHODS: We enrolled 544 ED patients who were admitted for symptoms of possible acute coronary syndrome after a nondiagnostic initial evaluation during a quality improvement trial at 2 university hospitals. Adverse events, inhospital treatment, and follow-up care were assessed by 30-day telephone interview and medical record review. We used a modified version of the Medical Outcomes Study Short Form 20 and the Duke Activity Status Index to assess functional status. To account for selection bias, we analyzed process and outcome variables after adjustment for the estimated propensity of being admitted to cardiology and predicted probability of acute cardiac ischemia. RESULTS: Overall, 34% of admitted patients had confirmed acute coronary syndrome. Patients admitted to a cardiology service were significantly more likely to undergo evaluation for ischemic heart disease than those admitted to a noncardiology service (adjusted odds ratio for noninvasive testing 2.7; 95% confidence interval 1.7 to 4.2) but were not more likely to receive recommended therapies. The incidence of ED revisits and rehospitalizations, functional status, and adverse cardiovascular events were similar in both groups. CONCLUSION: ED patients admitted for evaluation of possible acute coronary syndrome do not experience worsened short-term outcomes if admitted to a noncardiology service bed.
N1  - PUBM: Print-Electronic; DEP: 20070829; JID: 8002646; 2007/03/26 [received]; 2007/05/10 [revised]; 2007/05/17 [accepted]; aheadofprint
A3  - Anonymous
SN  - 1097-6760
AD  - Departments of Medicine and Epidemiology, University of Iowa Carver College of Medicine and College of Public Health (Katz); Center for Research in the Implementation of Innovative Strategies in Practice, Iowa City VA Medical Center, Iowa City, (TRUNCATED)
JF  - Annals of Emergency Medicine
JA  - Ann.Emerg.Med.
M1  - Journal
ER  - 

TY  - JOUR
ID  - 6377
A1  - Kojima,H.
T1  - Treatment of Depression in Patients with Coronary Heart Disease
Y1  - 2007
Y2  - Sep
VL  - 120
IS  - 9
SP  - e13
N1  - PUBM: Print; JID: 0267200; 2006/07/28 [received]; 2006/07/28 [accepted]; ppublish
A3  - Anonymous
SN  - 1555-7162
AD  - Faculty Development Fellow, University of Pittsburgh Department of Family Medicine, Pittsburgh, Penn.
JF  - The American Journal of Medicine
JA  - Am.J.Med.
M1  - Journal
ER  - 

TY  - JOUR
ID  - 6361
A1  - Konduracka,E.
A1  - Gackowski,A.
A1  - Rostoff,P.
A1  - Galicka-Latala,D.
A1  - Frasik,W.
A1  - Piwowarska,W.
T1  - Diabetes-specific cardiomyopathy in type 1 diabetes mellitus: no evidence for its occurrence in the era of intensive insulin therapy
Y1  - 2007
Y2  - Aug 31
AB  - Aims The incidence of diabetic cardiomyopathy, independent of arterial hypertension (AH) and coronary heart disease (CHD), remains controversial. The present study aimed to determine the influence of type 1 diabetes mellitus (T1DM) of long duration (>10 years) on myocardial function estimated by echocardiography (ECHO) and serum level of N-terminal pro-B type natriuretic peptide (NT-proBNP) in patients without CHD and AH. We also retrospectively investigated the relationship between the structural changes in the hearts of other deceased T1DM patients, and had their myocardial function echocardiographically assessed before death. Methods and results In 185 patients (96 males) with T1DM (mean duration 22.8 years) and 105 non-diabetic control subjects (57 males), detailed ECHO parameters and NT-proBNP were assessed. No significant differences were found between the respective groups. Histological studies of 17 hearts of deceased T1DM patients were carried out and retrospectively compared with their ECHO performed before death. Histological changes were identified, although without the signs of myocardial dysfunction on ECHO prior to death. Conclusion Even the application of echocardiographic, biochemical and morphologic techniques hardly gives sufficient grounds to believe that type 1 diabetes alone may actually precipitate myocardial dysfunction, despite long-term course of the disease and typical histological changes in the myocardium.
N1  - PUBM: Print-Electronic; DEP: 20070831; JID: 8006263; aheadofprint
A3  - Anonymous
SN  - 0195-668X
AD  - Department of Coronary Disease, Jagiellonian University School of Medicine, ul. Pradnicka 80, Krakow 31-202, Poland.
JF  - European heart journal
JA  - Eur.Heart J.
M1  - Journal
ER  - 

TY  - JOUR
ID  - 6367
A1  - Kotseva,K.
A1  - Stagmo,M.
A1  - De Bacquer,D.
A1  - De Backer,G.
A1  - Wood,D.
A1  - on behalf of EUROASPIRE II Study Group
T1  - Treatment potential for cholesterol management in patients with coronary heart disease in 15 European countries: Findings from the EUROASPIRE II survey
Y1  - 2007
Y2  - Aug 31
AB  - BACKGROUND: During the last decade, the evidence of beneficial effects of cholesterol lowering in patients with coronary heart disease (CHD) has been proven in several clinical trials. This has prompted international guidelines on prevention of CHD to include recommendations on dietary and pharmacological treatment of hyperlipidaemia with set goals on total- and LDL-cholesterol. METHODS: The first EUROASPIRE survey performed in 1995/1996 showed poor adherence to the European recommendations on lipid-lowering in patients with CHD. The second survey was carried out in 1999/2000 in 15 European countries and enrolled 8181 patients with CHD. Medical records were assessed and clinical examinations of risk factors including serum lipids were performed. The aim of this survey is to describe the treatment of hyperlipidaemia among CHD patients in Europe. RESULTS: The proportion of patients not reaching the target of 5.0mmol/l was 58.3% with significant variations between countries. The use of lipid-lowering drugs was relatively high (60.9%). However, the most frequently used doses of lipid-lowering agents were much lower than the doses of proven effect used in clinical trials. CONCLUSIONS: Although the treatment of hyperlipidaemia in CHD patients seems to be improving as compared to the first survey, a significant number of patients do not reach treatment goals. If the full potential of lipid-lowering therapy was utilised with all eligible patients treated and doses titrated correctly, more patients would benefit in terms of reduced morbidity and mortality of CHD.
N1  - PUBM: Print-Electronic; DEP: 20070831; JID: 0242543; 2007/01/23 [received]; 2007/06/19 [revised]; 2007/07/11 [accepted]; aheadofprint
A3  - Anonymous
SN  - 0021-9150
AD  - Cardiovascular Medicine, National Heart and Lung Institute, Imperial College London, Charing Cross Hospital 5th Floor, Laboratory Block, Fulham Palace Road, London W6 8RF, United Kingdom.
JF  - Atherosclerosis
JA  - Atherosclerosis
M1  - Journal
ER  - 

TY  - JOUR
ID  - 6388
A1  - Kume,T.
T1  - Echocardiography is necessary to confirm the presence and severity of valvular heart disease
Y1  - 2007
Y2  - Jul
VL  - 60
IS  - 8 Suppl
SP  - 647
EP  - 652
AB  - Cardiac auscultation remains the most important method of screening for valvular heart diseases. Echocardiography is recommended for symptomatic patients or even asymptomatic patients with heart murmurs. Echocardiography is one of the most important examinations for the diagnosis and assessment of severity of valvular heart diseases. The severity of the aortic or mitral stenosis can be defined with Doppler echocardiographic measurements of maximum jet velocity, mean transvalvular pressure gradient, which can be measured from the continuous-wave Doppler signal across the valve with the modified Bernoulli equation, and continuity equation valve area. Planimetry of the orifice area may be possible from the short-axis view. The mitral valve area can also be derived from Doppler echocardiography with the diastolic pressure half-time method. In addition to semiquantitative assessment of the severity of aortic or mitral regurgitation by color flow jet area by Doppler echocardiography, quantitative measurement of regurgitant volume, regurgitant fraction, and regurgitant orifice area can be performed. Indirect measures of severity of aortic regurgitation are helpful, using the rate of decline in regurgitant gradient measured by the slope of diastolic flow velocity, or using the degree of reversal in pulse wave velocity in the descending aorta
N1  - PUBM: Print; JID: 0413533; ppublish
CY  - Japan
A3  - Anonymous
SN  - 0021-5252
AD  - Department of Cardiology, Kawasaki Medical School, Kurashiki, Japan.
JF  - Kyobu geka.The Japanese journal of thoracic surgery
JA  - Kyobu Geka
M1  - Journal
ER  - 

TY  - JOUR
ID  - 6406
A1  - Lawlor,D. A.
A1  - Fraser,A.
A1  - Ebrahim,S.
A1  - Smith,G. D.
T1  - Independent associations of fasting insulin, glucose, and glycated haemoglobin with stroke and coronary heart disease in older women
Y1  - 2007
Y2  - Aug 28
VL  - 4
IS  - 8
SP  - e263
AB  - BACKGROUND: Evidence suggests that variations in fasting glucose and insulin amongst those without frank type 2 diabetes mellitus are important determinants of cardiovascular disease. However, the relative importance of variations in fasting insulin, glucose, and glycated haemoglobin as risk factors for cardiovascular disease in women without diabetes is unclear. Our aim was to determine the independent associations of fasting insulin, glucose, and glycated haemoglobin with coronary heart disease and stroke in older women. METHODS AND FINDINGS: We undertook a prospective cohort study of 3,246 British women aged 60-79 y, all of whom were free of baseline coronary heart disease, stroke, and diabetes, and all of whom had fasting glucose levels below 7 mmol/l. Fasting insulin and homeostasis model assessment for insulin sensitivity (HOMA-S) were linearly associated with a combined outcome of coronary heart disease or stroke (n = 219 events), but there was no association of fasting glucose or glycated haemoglobin with these outcomes. Results were similar for coronary heart disease and stroke as separate outcomes. The age, life-course socioeconomic position, smoking, and physical activity adjusted hazard ratio for a combined outcome of incident coronary heart disease or stroke per one standard deviation of fasting insulin was 1.14 (95% CI 1.02-1.33). Additional adjustment for other components of metabolic syndrome, low-density lipoprotein cholesterol, fasting glucose, and glycated haemoglobin had little effect on this result. CONCLUSIONS: Our findings suggest that in women in the 60-79 y age range, insulin resistance, rather than insulin secretion or chronic hyperglycaemia, is a more important risk factor for coronary heart disease and stroke. Below currently used thresholds of fasting glucose for defining diabetes, neither fasting glucose nor glycated haemoglobin are associated with cardiovascular disease.
N1  - PUBM: Print; JID: 101231360; 2007/04/04 [received]; 2007/07/18 [accepted]; ppublish
CY  - United States
A3  - Anonymous
SN  - 1549-1676
AD  - Department of Social Medicine, University of Bristol, Bristol, United Kingdom. d.a.lawlor@bristol.ac.uk
JF  - PLoS medicine
JA  - PLoS Med.
M1  - Journal
ER  - 

TY  - JOUR
ID  - 6365
A1  - Leblanc,J.
A1  - Heran,M.
T1  - Decision-making in unoperated adults with congenital heart disease: a difficult task
Y1  - 2007
Y2  - Aug 31
AB  - The authors present a 32-year-old lady with a diagnosis of VSD, pulmonary atresia and multiple aortopulmonary collateral arteries (MAPCAs), who was palliated successfully by stent implantation. This interventional procedure is discussed as well as the decision-making process in adult patients with unoperated congenital heart disease. Keywords: Catheter intervention; Adult congenital heart disease.
N1  - PUBM: Print-Electronic; DEP: 20070831; JID: 101158399; aheadofprint
A3  - Anonymous
SN  - 1569-9285
AD  - British Columbia Children's Hospital, Vancouver, BC, Canada.
JA  - Interact.Cardiovasc.Thorac.Surg.
M1  - Journal
ER  - 

TY  - JOUR
ID  - 6376
A1  - Lee,C. H.
A1  - Liu,P. Y.
A1  - Tsai,L. M.
A1  - Tsai,W. C.
A1  - Ho,M. T.
A1  - Chen,J. H.
A1  - Lin,L. J.
T1  - Characteristics of Hospitalized Patients with Atrial Fibrillation in Taiwan: A Nationwide Observation
Y1  - 2007
Y2  - Sep
VL  - 120
IS  - 9
SP  - 819.e1
EP  - 819.e7
AB  - PURPOSE: The aim of the study is to describe the nationwide epidemiological data for hospitalized patients with atrial fibrillation in Taiwan. METHODS: We collected information on hospitalized patients with discharge-diagnosed atrial fibrillation from 1997 through 2002 from the Taiwan National Health Insurance database. Patients were examined for temporal trends in the frequency of the disease, clinical characteristics, and in-hospital mortality. RESULTS: Of 162,340 patients (mean age, 73.8 years), 55.3% were men and 38.6% had a primary diagnosis of atrial fibrillation. The mean annual frequency of diagnosed atrial fibrillation was 127 per 100,000 persons. The frequency of atrial fibrillation rose from 91 (1997) to 150 (2002) per 100,000 persons (P /=80 years. The frequency was significantly higher in men than in women (137 vs 116 per 100,000; P <.001). The average in-hospital mortality rate was 9.3%. In-hospital mortality rate showed a decreasing trend (9.9% vs 7.6%; P = .003). Comorbidities of ischemic heart disease, valvular heart disease, hypertension, ischemic stroke, and congestive heart failure were predictors of higher mortality. CONCLUSIONS: This Taiwanese study showed a 1.65-fold increase in the frequency of diagnosed atrial fibrillation during the study period. The in-hospital mortality rate, however, declined. The frequency of atrial fibrillation was higher in men and the elderly. We should be more concerned about negative outcomes in hospitalized patients with atrial fibrillation and other coexisting cardiovascular conditions.
N1  - PUBM: Print-Electronic; DEP: 20070802; JID: 0267200; 2006/04/27 [received]; 2006/10/03 [revised]; 2006/10/05 [accepted]; 2007/08/02 [aheadofprint]; ppublish
A3  - Anonymous
SN  - 1555-7162
AD  - Department of Internal Medicine, National Cheng Kung University Hospital, Tainan, Taiwan.; Department of Internal Medicine, National Cheng Kung University Hospital Dou-Liou Branch, Yun-Lin, Taiwan.
JF  - The American Journal of Medicine
JA  - Am.J.Med.
M1  - Journal
ER  - 

TY  - JOUR
ID  - 6373
A1  - Marx,G. R.
A1  - Su,X.
T1  - Three-Dimensional Echocardiography in Congenital Heart Disease
Y1  - 2007
Y2  - May
VL  - 25
IS  - 2
SP  - 357
EP  - 365
AB  - Matrix array technology has brought three-dimensional echocardiography into the clinical practice of cardiology. Arguably, this advancement is most notable in the field of pediatric cardiology. Full-volume acquisitions now can be undertaken in the youngest of infants with excellent image quality. This article illustrates the clinical application of three-dimensional echocardiography in congenital heart disease.
N1  - PUBM: Print; JID: 8300331; ppublish
A3  - Anonymous
SN  - 0733-8651
AD  - Department of Cardiology, Children's Hospital Boston, Farley-2, 300 Longwood Avenue, Boston, MA 02115, USA.
JF  - Cardiology clinics
JA  - Cardiol.Clin.
M1  - Journal
ER  - 

TY  - JOUR
ID  - 6394
A1  - Masci,P. G.
A1  - Dymarkowski,S.
A1  - Bogaert,J.
T1  - Valvular heart disease: what does cardiovascular MRI add?
Y1  - 2007
Y2  - Aug 29
AB  - Although ischemic heart disease remains the leading cause of cardiac-related morbidity and mortality in the industrialized countries, a growing number of mainly elderly patients will experience a problem of valvular heart disease (VHD), often requiring surgical intervention at some stage. Doppler-echocardiography is the most popular imaging modality used in the evaluation of this disease entity. It encompasses, however, some non-negligible constraints which may hamper the quality and thus the interpretation of the exam. Cardiac catheterization has been considered for a long time the reference technique in this field, however, this technique is invasive and considered far from optimal. Cardiovascular magnetic resonance imaging (MRI) is already considered an established diagnostic method for studying ventricular dimensions, function and mass. With improvement of MRI soft- and hardware, the assessment of cardiac valve function has also turned out to be fast, accurate and reproducible. This review focuses on the usefulness of MRI in the diagnosis and management of VHD, pointing out its added value in comparison with more conventional diagnostic means.
N1  - PUBM: Print-Electronic; DEP: 20070829; JID: 9114774; 2007/03/22 [received]; 2007/07/12 [accepted]; 2007/06/26 [revised]; 2007/08/29 [aheadofprint]; aheadofprint
A3  - Anonymous
SN  - 0938-7994
AD  - Department of Radiology, Gasthuisberg University Hospital, 49 Herestraat, Leuven, 3000, Belgium, jan.bogaert@uz.kuleuven.ac.be.
JF  - European radiology
JA  - Eur.Radiol.
M1  - Journal
ER  - 

TY  - JOUR
ID  - 6396
A1  - Mohandas,B.
A1  - Mehta,J. L.
T1  - Lessons from hormone replacement therapy trials for primary prevention of cardiovascular disease
Y1  - 2007
Y2  - Sep
VL  - 22
IS  - 5
SP  - 434
EP  - 442
AB  - PURPOSE OF REVIEW: Coronary heart disease in women is a common cause of morbidity and mortality, particularly after menopause. It was thought that estrogen and progesterone protected women from coronary heart disease. The recommendations of the recent Women's Health Initiative, however, are that hormone replacement therapy should not be used for primary prevention of coronary heart disease in women. Here, we have made a comprehensive review of major studies and comment on the validity of this recommendation. We have also analyzed the importance of dietary modification in primary prevention. In addition, we have delineated the important predictors of cardiovascular disease in women from prior observational and clinical studies. RECENT FINDINGS: Recent major studies, including the Women's Health Initiative (WHI) and Heart and Estrogen/Progestin Replacement Study (HERS), studied the role of hormone replacement therapy in protecting women from coronary heart disease. These studies showed no significant reduction in coronary heart disease events. In addition, the dietary modification component of the Women's Health Initiative did not show any significant reduction in the incidence of coronary heart disease. SUMMARY: It can be summarized that hormone replacement is not generally recommended in postmenopausal women for primary prevention of coronary heart disease. Although the dietary modification trials did not show any significant reduction in the incidence of coronary heart disease, it is currently recommended to continue using a heart-healthy diet.
N1  - PUBM: Print; JID: 8608087; ppublish
CY  - United States
A3  - Anonymous
SN  - 0268-4705
AD  - Division of Cardiovascular Medicine, Department of Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
JF  - Current opinion in cardiology
JA  - Curr.Opin.Cardiol.
M1  - Journal
ER  - 

TY  - JOUR
ID  - 6364
A1  - Monteiro,A. J.
A1  - Canale,L. S.
A1  - Rangel,I.
A1  - Wetzel,E.
A1  - Pinto,D. F.
A1  - Barbosa,R. C.
A1  - Meier,M. A.
A1  - Marcial,M. L.
T1  - Surgical treatment of complete atrioventricular septal defect with the two-patch technique: early-to-mid follow-up
Y1  - 2007
Y2  - Aug 31
AB  - We report our results on surgical treatment of complete atrioventricular septal defects using the two-patch technique. Forty patients with complete atrioventricular septal defects were operated on in the period from November 1995 to January 2004 and retrospectively analyzed. The age at the time of surgery ranged from 4 months to 20 years old (average=18.8+/-37 months). Their weight ranged from 3 to 39 kg (average=7.6+/-5.8 kg). Associated tetralogy of Fallot was present in 20% of the cases (8 patients). Monitoring was complete until January 2007, corresponding to a follow-up ranging from 36 to 135 months (average=74+/-33.7 months). The surgical mortality rate was 2.5% and the hospital mortality rate was 5%. A third patient died from a brain abscess two years after surgery. Over the long term, 2 patients needed further operations: one was submitted to mitral plasty due to severe residual mitral insufficiency, 1 year later; the other underwent a resection of a sub-aortic membrane after 3 years. Differences were evaluated using the Student-t or Mann-Whitney tests. Surgical treatment of complete atrioventricular septal defect using the two-patch technique results in low morbidity and mortality in early-to-mid term follow up. Keywords: Atrioventricular defects; Tetralogy of Fallot; Congenital heart disease.
N1  - PUBM: Print-Electronic; DEP: 20070831; JID: 101158399; aheadofprint
A3  - Anonymous
SN  - 1569-9285
AD  - Pro-Cardiaco Hospital, Rio de Janiero, Brazil.
JA  - Interact.Cardiovasc.Thorac.Surg.
M1  - Journal
ER  - 

TY  - JOUR
ID  - 6375
A1  - Mumm,B.
A1  - Baumann,R.
A1  - Hyca,M.
T1  - Three-Dimensional Echo for the Assessment of Valvular Heart Disease
Y1  - 2007
Y2  - May
VL  - 25
IS  - 2
SP  - 283
EP  - 295
AB  - Three-dimensional echocardiography (3DE) is a valuable tool to be used in addition to and not instead of two-dimensional echocardiography by providing complementary information and improved quantitative accuracy and reproducibility compared with two-dimensional techniques. 3DE has the potential to become the standard echocardiographic examination procedure for the assessment of valvular disease. This article describes applications of 3DE.
N1  - PUBM: Print; JID: 8300331; ppublish
A3  - Anonymous
SN  - 0733-8651
AD  - TomTec Imaging Systems GmbH, Edisonstrasse 6, Unterschleissheim 85716, Germany.
JF  - Cardiology clinics
JA  - Cardiol.Clin.
M1  - Journal
ER  - 

TY  - JOUR
ID  - 6372
A1  - Nasir,K.
A1  - Shaw,L. J.
A1  - Liu,S. T.
A1  - Weinstein,S. R.
A1  - Mosler,T. R.
A1  - Flores,P. R.
A1  - Flores,F. R.
A1  - Raggi,P.
A1  - Berman,D. S.
A1  - Blumenthal,R. S.
A1  - Budoff,M. J.
T1  - Ethnic Differences in the Prognostic Value of Coronary Artery Calcification for All-Cause Mortality
Y1  - 2007
Y2  - Sep 4
VL  - 50
IS  - 10
SP  - 953
EP  - 960
AB  - OBJECTIVES: The purpose of this study was to evaluate the prognostic value of coronary artery calcium (CAC), a known marker of subclinical atherosclerosis, in a large, ethnically diverse cohort of 14,812 patients for the prediction of all-cause mortality. BACKGROUND: Disparities in case fatality rates for heart disease among ethnic groups are well known. In 2001, rates of death from heart disease were 30% higher among African Americans (AA) than non-Hispanic whites (NHW). Some of this variability may be due to differing pathophysiological mechanisms and effects of underlying atherosclerosis. METHODS: Ten-year death rates from all causes (total deaths = 505) were compared using risk-adjusted Cox proportional hazards models in AA (n = 637), Hispanic (HS, n = 1,334), Asian (AS, n = 1,065), and NHW (n = 11,776) populations. RESULTS: Ethnic minority patients were generally younger (0.3 to 4 years), more often persons with diabetes (p /=100 was highest in NHW (31%) and lowest for HS (18%) (p /=100 was highest in NHW (31%) and lowest for HS (18%) (p /=400 exceeding 16.1 (p /=400 had relative risk ratios from 7.9 to 9.0, whereas AS with CAC scores >/=1,000 had relative risk ratios 6.6-fold higher than NHW (p < 0.0001). CONCLUSIONS: Consistent with population evidence, AA with increasing burden of subclinical coronary artery disease were the highest-risk ethnic minority population. These data support a growing body of evidence noting substantial differences in cardiovascular risk by ethnicity.
N1  - PUBM: Print-Electronic; DEP: 20070820; JID: 8301365; 2007/01/23 [received]; 2007/03/08 [revised]; 2007/03/12 [accepted]; 2007/08/20 [aheadofprint]; ppublish
A3  - Anonymous
SN  - 1558-3597
AD  - Cardiac MRI PET CT Program, Massachusetts General Hospital Boston, Harvard School of Medicine, Boston, Massachusetts.
JF  - Journal of the American College of Cardiology
JA  - J.Am.Coll.Cardiol.
M1  - Journal
ER  - 

TY  - JOUR
ID  - 6405
A1  - Nonnenmacher,C.
A1  - Stelzel,M.
A1  - Susin,C.
A1  - Sattler,A. M.
A1  - Schaefer,J. R.
A1  - Maisch,B.
A1  - Mutters,R.
A1  - Flores-de-Jacoby,L.
T1  - Periodontal Microbiota in Patients With Coronary Artery Disease Measured by Real-Time Polymerase Chain Reaction: A Case-Control Study
Y1  - 2007
Y2  - Sep
VL  - 78
IS  - 9
SP  - 1724
EP  - 1730
AB  - Background: Recent data have shown that periodontal disease may increase the risk of occurrence of coronary heart disease in which inflammation initiated by bacteria and their compounds might be a common causal factor. This case-control study aimed at studying the relationship between periodontal disease and coronary artery disease (CAD) based on clinical and periodontal microbiologic parameters. Methods: A total of 90 male subjects, 48 to 80 years of age, were included in this study. Forty-five men had CAD (CAD+), which was confirmed by coronary angiography. Forty-five age-matched controls showed no history or symptoms of CAD (CAD-). All subjects underwent a clinical periodontal examination including assessment of tooth loss, probing depth, clinical attachment level, and bleeding on probing. In the CAD+ group, this examination took place 1 day before coronary angiography. Subgingival microbial samples were taken and evaluated by means of real-time polymerase chain reaction (RT-PCR) for the total amount of bacteria and the following periodontopathogens: Actinobacillus actinomycetemcomitans, Porphyromonas gingivalis, Prevotella intermedia, Parvimonas micra (formerly Micromonas micros), Dialister pneumosintes, and Campylobacter rectus. Results: Compared to control subjects, CAD+ subjects had significantly deeper pockets (2.28 mm versus 2.96 mm; P <0.001) and greater attachment loss (2.85 mm versus 3.65 mm; P <0.001), and this difference remained statistically significant after adjusting for smoking. No significant differences were observed between cases and controls with regard to the number of teeth present. P. intermedia was the only periodontal pathogen that showed significantly higher mean counts in CAD+ subjects compared to CAD- subjects. Higher counts of total bacteria, P. micra, D. pneumosintes, and C. rectus were found in the CAD- group. Conclusion: The results suggest that a relationship between periodontal disease and coronary heart disease exists, although P. intermedia was the only periodontopathogen related to CAD.
N1  - PUBM: Print; JID: 8000345; ppublish
A3  - Anonymous
SN  - 0022-3492
AD  - * Institute of Medical Microbiology and Hygiene, Philipps University Marburg, Marburg, Germany., dagger Department of Periodontology, School of Dentistry, Philipps University Marburg., double dagger Faculty of Dentistry - Periodontology, Federal(TRUNCATED)
JF  - Journal of periodontology
JA  - J.Periodontol.
M1  - Journal
ER  - 

TY  - JOUR
ID  - 6403
A1  - Parashar,S.
A1  - Vaccarino,V.
T1  - Depression and CHD Risk: How Should We Intervene?
Y1  - 2007
Y2  - Aug
VL  - 9
IS  - 4
SP  - 272
EP  - 277
AB  - Depression is common in the community and is a risk factor for the development of coronary heart disease (CHD). In patients with CHD, the prevalence of major depression is nearly 20% and the prevalence of minor depressive disorder is approximately 27%. When present in patients with existing CHD, depression is independently associated with worse outcome, including higher morbidity and mortality, and worse health status. Observational studies suggest that use of antidepressant medications in patients with CHD is associated with decreased risk of cardiovascular events. However, only one randomized controlled trial, the ENRICHD (Enhancing Recovery in Coronary Heart Disease) study, was designed to evaluate whether treatment of depression in patients with CHD can improve cardiac prognosis. Although the study showed that cognitive behavior therapy was better than usual care in improving depression, there was no improvement in all-cause mortality or recurrent cardiac events. There have been no clinical trials specifically designed to evaluate whether pharmacologic treatment of depression improves cardiovascular outcomes in patients with CHD. Thus, there is a clear need for additional trials testing interventions to improve cardiac prognosis based on treatment of depression. In the meantime, depression remains an important illness in its own right and deserves treatment. Safe and effective treatments of depression in patients with CHD include cognitive behavior therapy and selective serotonin reuptake inhibitors.
N1  - PUBM: Print; JID: 9815942; ppublish
CY  - United States
A3  - Anonymous
SN  - 1092-8464
AD  - Viola Vaccarino, MD, PhD Department of Medicine, Emory University, 49 Jesse Hill Jr. Drive, Atlanta, GA 30345, USA. susmita.parashar@emory.edu.
JF  - Current treatment options in cardiovascular medicine
JA  - Curr.Treat.Options Cardiovasc.Med.
M1  - Journal
ER  - 

TY  - JOUR
ID  - 6408
A1  - Pedersen,T. R.
T1  - Statin Therapy: Changing the Mode of Coronary Heart Disease
Y1  - 2007
Y2  - Aug 30
VL  - 109
IS  - 3
SP  - 154
EP  - 155
N1  - PUBM: Print-Electronic; DEP: 20070830; JID: 1266406; 2007/04/13 [received]; 2007/04/14 [accepted]; 2007/08/30 [aheadofprint]; aheadofprint
A3  - Anonymous
SN  - 1421-9751
AD  - Ulleval University Hospital, Oslo, Norway.
JF  - Cardiology
JA  - Cardiology
M1  - Journal
ER  - 

TY  - JOUR
ID  - 6363
A1  - Ravassa,S.
A1  - Gonzalez,A.
A1  - Lopez,B.
A1  - Beaumont,J.
A1  - Querejeta,R.
A1  - Larman,M.
A1  - Diez,J.
T1  - Upregulation of myocardial Annexin A5 in hypertensive heart disease: association with systolic dysfunction
Y1  - 2007
Y2  - Aug 31
AB  - Aims To investigate whether Annexin A5 (AnxA5) is related to hypertensive heart disease (HHD) and whether this relation is dependent of apoptosis. Methods and results Hypertensives without cardiac abnormalities (stage A), with left ventricular hypertrophy (LVH) (stage B), and with LVH and clinical manifestations of chronic HF (stage C), were studied. AnxA5 was quantified in endomyocardial biopsies by real time RT-PCR, Western blot, and immunohistochemistry, and apoptosis by DNA fragmentation, caspase-3 activation, and PARP and Bax/Bcl-2 ratios. Plasma AnxA5 was measured by ELISA in samples from the coronary sinus and the antecubital vein. Although AnxA5 mRNA did not change, myocardial and plasma AnxA5 were increased in hypertensives stages B and C compared with normotensives and hypertensives stage A. Myocardial AnxA5 was inversely correlated with parameters assessing systolic function in all hypertensives, this association being independent of apoptosis. Myocardial AnxA5 was directly correlated with plasma AnxA5. Plasma AnxA5 was inversely correlated with systolic function in all hypertensives. Conclusion This cross-sectional study shows that myocardial AnxA5 upregulation is associated with HHD and impairment of systolic function in hypertensive patients, this association being independent of apoptosis. Plasma AnxA5 can be a marker of myocardial AnxA5 upregulation and systolic dysfunction in patients with HHD.
N1  - PUBM: Print-Electronic; DEP: 20070831; JID: 8006263; aheadofprint
A3  - Anonymous
SN  - 0195-668X
AD  - Division of Cardiovascular Sciences, Centre for Applied Medical Research, University of Navarra, Pamplona, Spain.
JF  - European heart journal
JA  - Eur.Heart J.
M1  - Journal
ER  - 

TY  - BOOK
ID  - 6354
A1  - Rowling,J. K.
T1  - Harry Potter and the half-blood prince
Y1  - 2005
N1  - Provisional Circ record
CY  - New York : Scholastic
A3  - Anonymous
M1  - Book, Whole
ER  - UGL PRON 999 RO-317 *H BK

TY  - BOOK
ID  - 6355
A1  - Rowling,J. K.
T1  - Harry Potter and the half-blood prince
Y1  - 2005
SP  - 607
KW  - England
KW  - Juvenile fiction
KW  - Potter, Harry (Fictitious character)
KW  - Wizards
KW  - Magic
KW  - Schools
KW  - Hogwarts School of Witchcraft and Wizardry (Imaginary place)
KW  - Fantasy fiction
KW  - Juvenile literature
AB  - Harry Potter and the Half-Blood Prince brings us Harry Potter's sixth year at Hogwarts School of Witchcraft and Wizardry as Lord Voldemort becomes ever more powerful with his followers increasing day by day in this continuing battle between good and evil.
N1  - J.K. Rowling.; Sequel to: Harry Potter and the Order of the Phoenix.; SPEC 1: First edition, in dust jacket. Adult issue in black cloth binding.; SPEC 2: First edition, in dust jacket. Children's issue in pictorial binding.
PB  - Bloomsbury Pub.
CY  - London
A3  - Anonymous
SN  - 0747581088; 074758110X
M1  - Book, Whole
ER  - SPEC CHIL PR 6068 .O93 H28 2005c; SPEC CHIL PR 6068 .O93 H28 2005ch; UGL PR 6068 .O93 H28 2005 BK

TY  - BOOK
ID  - 6359
A1  - Rowling,J. K.
T1  - Harry Potter : y la orden del Fâenix
Y1  - 2004
VL  - 5
SP  - 893
KW  - Potter, Harry (Fictitious character)
KW  - Juvenile fiction
KW  - Hogwarts School of Witchcraft and Wizardry (Imaginary place)
KW  - Wizards
KW  - Magic
KW  - Schools
KW  - England
KW  - Coming of age
KW  - Magia
KW  - Novela juvenil
KW  - Escuelas
KW  - Inglaterra
KW  - Novela inglesa Siglo XX
KW  - Traducciones al espaänol
KW  - Juvenile literature
AB  - Las tediosas vacaciones de verano en la casa de los tâios de Harry todavâia no han acabado cuando Harry presiente que algo extraäno estâa sucediento en academia Hogwarts. Cuando por fin comienza otro curso en el famoso colegio de magia y hechicerâia, sus temores vuelven realidad.; As Harry faces his upcoming fifth year at Hogwarts Academy, there are increasing rumors of dark times coming and of Lord Voldemort's return to power, and a secret anti-Voldemort society, The Order of the Phoenix, begins meeting again.
N1  - J.K. Rowling ; [traducciâon, Gemma Rovira Ortega].; Secuela a: Harry Potter y el câaliz de fuego = Sequel to: Harry Potter and the goblet of fire.; Translation of: Harry Potter and the Order of the Phoenix.; SPEC: First edition, paperback.
T2  - Harry Potter
VL  - 1a.
PB  - Salamandra
CY  - Barcelona
A3  - Anonymous
SN  - 8478888845
M1  - Book, Whole
ER  - SPEC CHIL PR 6068 .O93 H277 2004

TY  - BOOK
ID  - 6344
A1  - Rowling,J. K.
T1  - Harry Potter and the chamber of secrets
Y1  - 1999
SP  - 341
KW  - Wizards
KW  - Fiction
KW  - Magic
KW  - Schools
KW  - England
AB  - When the Chamber of Secrets is opened again at the Hogswart School for Witchcraft and Wizardry, second-year student Harry Potter finds himself in danger from a dark power that has once more been released on the school.
N1  - by J.K. Rowling ; illustrations by Mary Grandpre.; Sequel to: Harry Potter and the sorcerer's stone.
VL  - 1st American
PB  - Arthur A. Levine Books
CY  - New York
A3  - Anonymous
SN  - 0439064864
M1  - Book, Whole
ER  - FLINT MAIN PR 6068 .O93 H25

TY  - BOOK
ID  - 6345
A1  - Rowling,J. K.
T1  - Harry Potter and the prisoner of Azkaban
Y1  - 1999
SP  - 435
KW  - Wizards
KW  - Fiction
KW  - Magic
KW  - Schools
KW  - England
AB  - During his third year at Hogwarts School for Witchcraft and Wizardry, Harry Potter must confront the devious and dangerous wizard responsible for his parents' deaths.
N1  - by J.K. Rowling.; Sequel to: Harry Potter and the Chamber of Secrets.
PB  - Arthur A. Levine Books
CY  - New York
A3  - Anonymous
SN  - 0439136350; 0439136369
M1  - Book, Whole
ER  - FLINT MAIN PR 6068 .O93 H28

TY  - BOOK
ID  - 6357
A1  - Rowling,J. K.
T1  - Harry Potter and the Prisoner of Azkaban-Advanced
Y1  - 1999
N1  - Shelved 8B
A3  - Anonymous
M1  - Book, Whole
ER  - SPEC SCLSPC041130-03 BK

TY  - BOOK
ID  - 6348
A1  - Rowling,J. K.
T1  - Harry Potter and the Order of the Phoenix
A3  - Anonymous
M1  - Book, Whole
ER  - UGL PRON BK; UGL 999 RO-293 *H

TY  - BOOK
ID  - 6360
A1  - Rowling,J. K.
A1  - Gabunian,Davit°
T1  - Hari Poteri da Azkabanis tqve
Y1  - 2004
SP  - 351
KW  - Potter, Harry (Fictitious character)
KW  - Juvenile fiction
KW  - Wizards
KW  - Magic
KW  - Hogwarts School of Witchcraft and Wizardry (Imaginary place)
KW  - Schools
KW  - England
KW  - Fiction
AB  - During his third year at Hogwarts School for Witchcraft and Wizardry, Harry Potter must confront the devious and dangerous wizard responsible for his parents' deaths.
N1  - J. K. Roulingi ; inglisuridan t°argmna Davit° Gabunian.; Sequel: Hari Poteri da c°ec°xlovani t°asi.; Sequel to: Hari Poteri da saidumlo ot°axi.
PB  - Bakur Sulakauris gamomc°emloba
CY  - T°bilisi
A3  - Anonymous
SN  - 9994030140
M1  - Book, Whole
ER  - SPEC CHIL PR 6068 .O93 H249 2004

TY  - BOOK
ID  - 6340
A1  - Rowling,J. K.
A1  - Gosling,William A.
T1  - Harry Potter and the prisoner of Azkaban
Y1  - 1999
SP  - 435
KW  - Potter, Harry (Fictitious character)
KW  - Juvenile fiction
KW  - Hogwarts School of Witchcraft and Wizardry (Imaginary place)
KW  - Magic
KW  - Schools
KW  - Wizards
KW  - England
KW  - Juvenile literature
AB  - During his third year at Hogwarts School for Witchcraft and Wizardry, Harry Potter must confront the devious and dangerous wizard responsible for his parents' deaths.
N1  - by J.K. Rowling.; Sequel to: Harry Potter and the Chamber of Secrets.; SPEC: Gift of William A. Gosling. First American edition, first printing, in dust jacket.
PB  - Arthur A. Levine Books
CY  - New York
A3  - Anonymous
SN  - 0439136350; 0439136369
M1  - Book, Whole
ER  - HATCH GRAD 828 R8838pr; HATCH JUV PZ 7 .R883 1999; SPEC CHIL PR 6068 .O93 H24 1999c; UGL PR 6068 .O93 H24 1999c BK

TY  - BOOK
ID  - 6356
A1  - Rowling,J. K.
A1  - GrandPrâe,Mary
T1  - Harry Potter and the Order of the Phoenix
Y1  - 2004
Y2  - 2003
SP  - 870
KW  - Potter, Harry (Fictitious character)
KW  - Juvenile fiction
KW  - Wizards
KW  - Magic
KW  - Schools
KW  - Hogwarts School of Witchcraft and Wizardry (Imaginary place)
KW  - England
KW  - Juvenile literature
AB  - Harry is in his fifth year at Hogwarts as the adventures continue. He faces challenges at every turn, from the dark threat of he-who-must-not-be-named and the unreliability of the government of the magical world to the rise of Ron Weasley as the keeper of the Gryffindor Quidditch Team. Along the way he learns about the strength of his friends, the fierceness of his enemies, and the meaning of sacrifice.
N1  - 9780439358071; by J.K. Rowling ; illustrations by Mary Grandprâe.; Sequel to: Harry Potter and the goblet of fire.; Dudley demented -- Peck of owls -- Advance guard -- Number twelve, Grimmauld Place -- Order of the Phoenix -- Noble and most ancient house of black -- Ministry of magic -- Hearing -- Woes of Mrs. Weasley -- Luna Lovegood -- Sorting hat's new song -- Professor Umbridge -- Detention with Dolores -- Percy and Padfoot -- Hogwarts high inquisitor - In the hog's head -- Educational decree number twenty-four -- Dumbledore's army -- Lion and the serpent -- Hagrid's tale -- Eye of the snake -- St. Mungo's hospital for magical maladies and injuries -- Christmas on the closed ward -- Occlumency -- Beetle at bay -- Seen and unforeseen -- Centaur and the sneak -- Snape's worst memory -- Career advice -- Grawp -- O.W.L.s -- Out of the fire -- Fight and flight -- Department of mysteries -- Beyond the veil -- Only one he ever feared -- Lost prophecy -- Second war begins.; SPEC: First Scholastic trade paperback printing.
PB  - Scholastic, Inc.
CY  - New York
A3  - Anonymous
SN  - 0439358078
M1  - Book, Whole
ER  - SPEC CHIL PR 6068 .O93 H27 2004

TY  - BOOK
ID  - 6351
A1  - Rowling,J. K.
A1  - GrandPrâe,Mary
T1  - Harry Potter and the prisoner of Azkaban
Y1  - 1999
SP  - 431
KW  - Potter, Harry (Fictitious character)
KW  - Juvenile fiction
KW  - Hogwarts School of Witchcraft and Wizardry (Imaginary place)
KW  - Wizards
KW  - Magic
KW  - Schools
KW  - England
KW  - Juvenile literature
N1  - By J.K. Rowling ; illustrations by Mary GrandPrâe.; "Uncorrected proofs" -- Half title page.; SPEC: Advance uncorrected proofs, paperback.
VL  - Advance reader's
PB  - Arthur A Levine Books
CY  - New York
A3  - Anonymous
SN  - 0439136350
M1  - Book, Whole
ER  - SPEC RCLC PR 6068 .O93 H24 1999ca

TY  - BOOK
ID  - 6353
A1  - Rowling,J. K.
A1  - GrandPrâe,Mary
A1  - Gosling,William A.
T1  - Harry Potter and the half-blood prince
Y1  - 2005
SP  - 652
KW  - Potter, Harry (Fictitious character)
KW  - Juvenile fiction
KW  - Hogwarts School of Witchcraft and Wizardry (Imaginary place)
KW  - Wizards
KW  - Magic
KW  - Fiction
KW  - Schools
KW  - England
KW  - Fantasy fiction
KW  - Juvenile literature
AB  - Harry Potter and the Half-Blood Prince brings us Harry Potter's sixth year at Hogwarts School of Witchcraft and Wizardry as Lord Voldemort becomes ever more powerful with his followers increasing day by day in this continuing battle between good and evil. Harry searches for the full and complex story of the boy who became Lord Voldemort, and thereby finds what may be his only vulnerability.
N1  - by J.K. Rowling ; illustrations by Mary GrandPrâe.; "Year 6 -- spine.; The other minister -- Spinner's end -- Will and won't -- Horace Slughorn -- An excess of phlegm -- Draco's detour -- The slug club -- Snape victorious -- The half-blood prince -- The house of gaunt -- Hermione's helping hand -- Silver and opals -- The secret riddle -- Felix Felicis -- The unbreakable vow -- Very frosty Christmas -- A sluggish memory -- Birthday surprises -- Elf tails -- Lord Voldemort's request -- The unknownable room -- After the burial -- Horcruxes -- Sectumsempra -- The seer overheard -- The cave -- The lightning-struck tower -- Flight of the prince -- The Phoenix lament -- The white tomb.; SPEC: Gift of William A. Gosling. First American edition, first printing, in dust jacket.
VL  - 1st American
PB  - Arthur A. Levine Books
CY  - New York
A3  - Anonymous
SN  - 0439784549
M1  - Book, Whole
ER  - HATCH JUV PZ 7 .R886 2005; SPEC CHIL PR 6068 .O93 H28 2005

TY  - BOOK
ID  - 6337
A1  - Rowling,J. K.
A1  - GrandPrâe,Mary
A1  - Gosling,William A.
T1  - Harry Potter and the Order of the Phoenix
Y1  - 2003
SP  - 870
KW  - Potter, Harry (Fictitious character)
KW  - Juvenile fiction
KW  - Wizards
KW  - Magic
KW  - Schools
KW  - Hogwarts School of Witchcraft and Wizardry (Imaginary place)
KW  - England
KW  - Fantasy fiction, Juvenile
KW  - Juvenile literature
AB  - When the government of the magic world and authorities at Hogwarts School of Witchcraft and Wizardry refuse to believe in the growing threat of a freshly revived Lord Voldemort, fifteen-year-old Harry Potter finds support from his loyal friends in facing the evil wizard and other new terrors.
N1  - by J.K. Rowling ; illustrations by Mary GrandPrâe.; "Year 5"--Spine.; SPEC 1: Gift of William A. Gosling. First American edition, first printing, in dust jacket.; SPEC 2: No edition statement on verso of title page. All black paper binding. Measures 22 cm. but carries the same ISBN.
VL  - 1st American
PB  - Arthur A. Levine Books
CY  - New York, NY
A3  - Anonymous
SN  - 043935806X
M1  - Book, Whole
ER  - HATCH JUV PR 6068 .O93 H27 2003; SPEC CHIL PR 6068 .O93 H27 2003; SPEC CHIL PR 6068 .O93 H27 2003b; UGL PR 6068 .O93 H27 2003 BK

TY  - BOOK
ID  - 6341
A1  - Rowling,J. K.
A1  - GrandPrâe,Mary
A1  - Gosling,William A.
T1  - Harry Potter and the goblet of fire
Y1  - 2000
SP  - 734
KW  - Potter, Harry (Fictitious character)
KW  - Juvenile fiction
KW  - Wizards
KW  - Magic
KW  - Hogwarts School of Witchcraft and Wizardry (Imaginary place)
KW  - Schools
KW  - England
KW  - Fantasy fiction
KW  - Juvenile
KW  - Juvenile literature
AB  - Fourteen-year-old Harry Potter joins the Weasleys at the Quidditch World Cup, then enters his fourth year at Hogwarts Academy where he is mysteriously entered in an unusual contest that challenges his wizarding skills, friendships and character, amid signs that an old enemy is growing stronger.
N1  - by J.K. Rowling ; illustrations by Mary GrandPrâe.; "Year 4"--Spine.; Sequel to: Harry Potter and the prisoner of Azkaban.; SPEC: Gift of William A. Gosling. First American edition, first printing, in dust jacket.
VL  - 1st American
PB  - Arthur A. Levine Books
CY  - New York
A3  - Anonymous
SN  - 0439139597
M1  - Book, Whole
ER  - HATCH JUV PZ 7 .R884 2000; SPEC CHIL PR 6068 .O93 H26 2000; UGL PR 6068 .O93 H26 2000 BK

TY  - BOOK
ID  - 6339
A1  - Rowling,J. K.
A1  - Grandprâe,Mary
A1  - Gosling,William A.
T1  - Harry Potter and the chamber of secrets
Y1  - 1999
SP  - 341
KW  - Potter, Harry (Fictitious character)
KW  - Juvenile fiction
KW  - Wizards
KW  - Schools
KW  - Hogwarts School of Witchcraft and Wizardry (Imaginary place)
KW  - Magic
KW  - England
KW  - Juvenile literature
AB  - When the Chamber of Secrets is opened again at the Hogswart School for Witchcraft and Wizardry, second-year student Harry Potter finds himself in danger from a dark power that has once more been released on the school.
N1  - by J.K. Rowling ; illustrations by Mary Grandprâe.; Sequel to: Harry Potter and the sorcerer's stone.; SPEC: Gift of William A. Gosling. First American edition, third printing, in dust jacket.
VL  - 1st American
PB  - Arthur A. Levine Books
CY  - New York
A3  - Anonymous
SN  - 0439064864
M1  - Book, Whole
ER  - HATCH JUV PZ 7 .R882 1999; SPEC CHIL PR 6068 .O93 H22 1999; UGL PR 6068 .O93 H22 1999 BK

TY  - BOOK
ID  - 6322
A1  - Rowling,J. K.
A1  - Grandprâe,Mary
A1  - Gosling,William A.
T1  - Harry Potter and the sorcerer's stone
Y1  - 1998
SP  - 309
KW  - Potter, Harry (Fictitious character)
KW  - Juvenile fiction
KW  - Hogwarts School of Witchcraft and Wizardry (Imaginary place)
KW  - Wizards
KW  - Schools
KW  - Magic
KW  - England
KW  - Juvenile literature
AB  - Rescued from the outrageous neglect of his aunt and uncle, a young boy with a great destiny proves his worth while attending Hogwarts School for Wizards and Witches.
N1  - by J.K. Rowling ; illustrations by Mary Grandprâe.; Sequel: Harry Potter and the Chamber of Secrets.; SPEC 1: Gift of William A. Gosling. First American edition, eighth printing, in dust jacket.; SPEC 2: Gift of William, A. Gosling. First American edition, 49th printing produced in Mexico, in dust jacket.
VL  - 1st American
PB  - A.A. Levine Books
CY  - New York
A3  - Anonymous
SN  - 0590353403; 059035342X
M1  - Book, Whole
ER  - HATCH JUV PZ 7 .R88 1998; SPEC CHIL PR 6068 .O93 .H2 1998; SPEC CHIL PR 6068 .O93 H2 1998b; UGL PR 6068 .O93 H2 1998 BK

TY  - BOOK
ID  - 6338
A1  - Rowling,J. K.
A1  - Grandprâe,Mary
A1  - Gosling,William A.
T1  - Harry Potter and the sorcerer's stone
Y1  - 1998
SP  - 309
KW  - Potter, Harry (Fictitious character)
KW  - Juvenile fiction
KW  - Hogwarts School of Witchcraft and Wizardry (Imaginary place)
KW  - Wizards
KW  - Schools
KW  - Magic
KW  - England
KW  - Juvenile literature
AB  - Rescued from the outrageous neglect of his aunt and uncle, a young boy with a great destiny proves his worth while attending Hogwarts School for Wizards and Witches.
N1  - by J.K. Rowling ; illustrations by Mary Grandprâe.; Sequel: Harry Potter and the Chamber of Secrets.; SPEC 1: Gift of William A. Gosling. First American edition, eighth printing, in dust jacket.; SPEC 2: Gift of William, A. Gosling. First American edition, 49th printing produced in Mexico, in dust jacket.
VL  - 1st American
PB  - A.A. Levine Books
CY  - New York
A3  - Anonymous
SN  - 0590353403; 059035342X
M1  - Book, Whole
ER  - HATCH JUV PZ 7 .R88 1998; SPEC CHIL PR 6068 .O93 .H2 1998; SPEC CHIL PR 6068 .O93 H2 1998b; UGL PR 6068 .O93 H2 1998 BK

TY  - BOOK
ID  - 6347
A1  - Rowling,J. K.
A1  - GrandPre,Mary
T1  - Harry Potter and the Order of the Phoenix
Y1  - 2003
SP  - 870
KW  - Wizards
KW  - Fiction
KW  - Magic
KW  - Schools
KW  - Coming of age
KW  - Potter, Harry (Fictitious character)
KW  - Juvenile fiction
KW  - Hogwarts School of Witchcraft and Wizardry (Imaginary place)
KW  - England
KW  - Fantasy fiction, Juvenile
KW  - Juvenile materials
AB  - When the government of the magic world and authorities at Hogwarts School of Witchcraft and Wizardry refuse to believe in the growing threat of a freshly revived Lord Voldemort, fifteen-year-old Harry Potter finds support from his loyal friends in facing the evil wizard and other new terrors.
N1  - by J.K. Rowling ; illustrations by Mary GrandPre.; "Year 5"--Spine.; Sequel to: Harry Potter and the goblet of fire.
VL  - 1st American
PB  - Arthur A. Levine Books
CY  - New York, NY
A3  - Anonymous
SN  - 043935806X
M1  - Book, Whole
ER  - FLINT MAIN PR 6068 .O93 H27

TY  - BOOK
ID  - 6346
A1  - Rowling,J. K.
A1  - GrandPre,Mary
T1  - Harry Potter and the goblet of fire
Y1  - 2000
SP  - 734
KW  - Wizards
KW  - Juvenile fiction
KW  - Magic
KW  - Hogwarts School of Witchcraft and Wizardry (Imaginary place)
KW  - Schools
KW  - Fiction
KW  - England
KW  - Fantasy fiction
KW  - Juvenile
AB  - Fourteen-year-old Harry Potter joins the Weasleys at the Quidditch World Cup, then enters his fourth year at Hogwarts Academy where he is mysteriously entered in an unusual contest that challenges his wizarding skills, friendships and character, amid signs that an old enemy is growing stronger.
N1  - by J.K. Rowling ; illustrations by Mary GrandPre.; "Year 4"--Spine.; Sequel to: Harry Potter and the prisoner of Azkaban.
VL  - 1st American
PB  - Arthur A. Levine Books
CY  - New York
A3  - Anonymous
SN  - 0439139597
M1  - Book, Whole
ER  - FLINT MAIN PR 6068 .O93 H26

TY  - BOOK
ID  - 6323
A1  - Rowling,J. K.
A1  - GrandPre,Mary
T1  - Harry Potter and the sorcerer's stone
Y1  - 1998
SP  - 309
KW  - Witches
KW  - Fiction
KW  - Wizards
KW  - Schools
KW  - England
AB  - Rescued from the outrageous neglect of his aunt and uncle, a young boy with a great destiny proves his worth while attending Hogwarts School for Wizards and Witches.
N1  - by J.K. Rowling ; illustrations by Mary GrandPre.; Sequel: Harry Potter and the Chamber of Secrets.
VL  - 1st American
PB  - A.A. Levine Books
CY  - New York
A3  - Anonymous
SN  - 0590353403; 059035342X
M1  - Book, Whole
ER  - FLINT MAIN PR 6068 .O93 H3

TY  - BOOK
ID  - 6343
A1  - Rowling,J. K.
A1  - GrandPre,Mary
T1  - Harry Potter and the sorcerer's stone
Y1  - 1998
SP  - 309
KW  - Witches
KW  - Fiction
KW  - Wizards
KW  - Schools
KW  - England
AB  - Rescued from the outrageous neglect of his aunt and uncle, a young boy with a great destiny proves his worth while attending Hogwarts School for Wizards and Witches.
N1  - by J.K. Rowling ; illustrations by Mary GrandPre.; Sequel: Harry Potter and the Chamber of Secrets.
VL  - 1st American
PB  - A.A. Levine Books
CY  - New York
A3  - Anonymous
SN  - 0590353403; 059035342X
M1  - Book, Whole
ER  - FLINT MAIN PR 6068 .O93 H3

TY  - BOOK
ID  - 6358
A1  - Rowling,J. K.
A1  - Nic Mhaolain,Maire
T1  - Harry Potter agus an Orchloch
Y1  - 2004
SP  - 262
KW  - Potter, Harry (Fictitious character)
KW  - Juvenile fiction
KW  - Hogwarts School of Witchcraft and Wizardry (Imaginary place)
KW  - Wizards
KW  - Magic
KW  - Schools
KW  - England
KW  - Fantasy fiction
KW  - Juvenile literature
N1  - J.K. Rowling ; Maire Nic Mhaolain a d'aistrigh.; Originally published under the title "Harry Potter and the Philosopher's Stone", in London by Bloomsbury in London in 1997.; SPEC: First printing, in dust jacket.
PB  - Bloomsbury
CY  - London
A3  - Anonymous
SN  - 074757166X; 1582348286
M1  - Book, Whole
ER  - SPEC CHIL PR 6068 .O93 .H209 2004

TY  - JOUR
ID  - 6389
A1  - Sakuma,H.
T1  - Cardiac magnetic resonace imaging
Y1  - 2007
Y2  - Jul
VL  - 60
IS  - 8 Suppl
SP  - 635
EP  - 641
AB  - Cardiac magnetic resonance (MR) imaging has been recognized as reliable means for accurate evaluation of cardiac anatomy and ventricular function. Late gadolinium-enhanced MR imaging can clearly delineate subendocardial infarction, and the assessment of transmural extent of infarction on late enhanced MR imaging has proved to be useful in predicting functional recovery of dysfunctional myocardium in patients after myocardial infarction. Stress first-pass contrast enhanced myocardial perfusion MR imaging can detect subendocardial ischemia, and recent studies demonstrated the high diagnostic accuracy of stress myocardial perfusion MR imaging in detecting significant coronary artery diseases. By combining stress perfusion MR imaging and late gadolinium MR imaging, infarcted myocardium and ischemic but viable myocardium can be differentiated. Free breathing, whole heart coronary MR angiography has recently been introduced as a method that can detect coronary artery stenosis, with the diagnostic accuracy comparable to 16-slice computed tomography (CT). MR flow measurement is useful in quantifying valvular regurgitation volume, shunt volume in congenital heart diseases, and blood flow in coronary artery bypass grafts. Cardiac MR imaging can play a pivotal role in managing patients with ischemic heart diseases.
N1  - PUBM: Print; JID: 0413533; ppublish
CY  - Japan
A3  - Anonymous
SN  - 0021-5252
AD  - Department of Radiology, Mie University Hospital, Tsu, Japan.
JF  - Kyobu geka.The Japanese journal of thoracic surgery
JA  - Kyobu Geka
M1  - Journal
ER  - 

TY  - JOUR
ID  - 6362
A1  - Schoenberg,N. E.
A1  - Kim,H.
A1  - Edwards,W.
A1  - Fleming,S. T.
T1  - Burden of Common Multiple-Morbidity Constellations on Out-of-Pocket Medical Expenditures Among Older Adults
Y1  - 2007
Y2  - Aug
VL  - 47
IS  - 4
SP  - 423
EP  - 437
AB  - PURPOSE: On average, adults aged 60 years or older have 2.2 chronic diseases, contributing to the over 60 million Americans with multiple morbidities. We aimed to understand the financial implications of the most frequent multiple morbidities among older adults. DESIGN AND METHODS: We analyzed Health and Retirement Study data, determining out-of-pocket medical expenses from 1998 and 2002 separately and examining differences in the impact of multiple-morbidity constellations on these expenses. We paid particular attention to the most common disease constellations-hypertension, arthritis, and heart disease. RESULTS: An increasing prevalence of multiple morbidity (58% compared with 70% of adults had two or more chronic conditions in 1998 and 2002, respectively) was accompanied by escalating out-of-pocket expenditures ($2,164 in 1998, increasing by 104% to $3,748 in 2002). Individuals with two, three, and four chronic conditions had health care expenditure increases of 41%, 85%, and 100%, respectively, over 4 years. Such patterns were particularly noticeable among the oldest old, those with higher educational attainment, and women, although having supplementary health insurance or Medicaid mitigated these expenses. Finally, there were significant differences in out-of-pocket expenditure levels among the multiple-morbidity combinations. IMPLICATIONS: Increasing rates of multiple morbidities in conjunction with escalating health care costs and stable or declining incomes among elders warrant creative attention from providers, researchers, and policy makers. Further understanding how specific multiple-morbidity constellations impact out-of-pocket spending moves us closer to effective interventions to support vulnerable elders.
N1  - PUBM: Print; JID: 0375327; ppublish
A3  - Anonymous
SN  - 0016-9013
AD  - Department of Behavioral Science, University of Kentucky, 125 College of Medicine Office Building, Lexington, KY 40536-0086. nesch@uky.edu.
JF  - The Gerontologist
JA  - Gerontologist
M1  - Journal
ER  - 

TY  - JOUR
ID  - 6401
A1  - Schooling,C. M.
A1  - Jiang,C.
A1  - Lam,T. H.
A1  - Thomas,G. N.
A1  - Heys,M.
A1  - Lao,X.
A1  - Zhang,W.
A1  - Adab,P.
A1  - Cheng,K. K.
A1  - Leung,G. M.
T1  - Height, Its Components, and Cardiovascular Risk Among Older Chinese: A Cross-Sectional Analysis of the Guangzhou Biobank Cohort Study
Y1  - 2007
Y2  - Aug 29
AB  - Objectives. Better childhood conditions, inferred from height and specifically leg length, are usually protective against ischemic heart disease and its risk factors in Western countries. In other geo-ethnic populations, height is less clearly protective, casting doubt on there being a biological etiology. To clarify the role of childhood conditions, we examined the associations of height and its components with cardiovascular risk among older Chinese people. Methods. We used multivariable regression to examine the associations of height and its components with blood pressure, lipid profile, and diabetes in 10413 older Chinese adults (mean age=64.6 years). Results. After we adjusted for age, gender, socioeconomic status, and lifestyle habits, greater sitting height was associated with diabetes and dyslipidemia. Longer legs were associated with lower pulse pressure and lower low-density lipoprotein cholesterol. Conclusions. We provide indirect anthropometric evidence for the role of prepubertal and pubertal variables on cardiovascular risk. Pubertal variables are stronger but may be influenced by osteoporotic decline in old age. Further research should establish whether the observed relations are ethnically specific or relate to the stage or trajectory of socioeconomic development.
N1  - PUBM: Print-Electronic; DEP: 20070829; JID: 1254074; aheadofprint
A3  - Anonymous
SN  - 1541-0048
AD  - University of Hong Kong.
JF  - American Journal of Public Health
JA  - Am.J.Public Health
M1  - Journal
ER  - 

TY  - JOUR
ID  - 6380
A1  - Senkus-Konefka,E.
A1  - Jassem,J.
T1  - Cardiovascular effects of breast cancer radiotherapy
Y1  - 2007
Y2  - Aug 29
AB  - Cardiac toxicity has been implicated as the primary reason for excess non-breast cancer mortality in early breast cancer radiotherapy studies. Refinements in radiotherapy techniques have allowed for a considerable reduction of this risk in the majority of breast cancer patients. Recent large population-based studies confirmed an increase of cardiovascular death risk in patients irradiated for cancer of the left breast and in individuals exposed to relatively low (hitherto believed to be of no cardiovascular disease risk) doses of radiation, such as atomic bomb survivors or patients treated for various benign conditions. The issue of potential radiation-related cardiac damage may also be assuming a new significance due to the widespread use of other cardiotoxic agents, such as anthracyclines, paclitaxel and trastuzumab. The aim of this review is to summarize and critically analyze the available evidence on the impact of ionizing radiation on the cardiovascular system, with special attention to recent data demonstrating previously unrecognized adverse effects. This review discusses the pathology of radiation-related cardiovascular disease, its clinical presentation, risk factors and methods of assessment, as well as technical developments minimizing cardiac exposure. Epidemiological data are presented on the incidence of radiation-induced heart disease and cardiovascular mortality in various populations of patients irradiated for breast cancer and in individuals exposed to low radiation doses. Additionally, non-cardiac radiation-related vascular morbidity and mortality in breast cancer patients are addressed.
N1  - PUBM: Print-Electronic; DEP: 20070829; JID: 7502030; 2007/02/26 [received]; 2007/07/13 [revised]; 2007/07/16 [accepted]; aheadofprint
A3  - Anonymous
SN  - 0305-7372
AD  - Department of Oncology and Radiotherapy, Medical University of Gdansk, Debinki 7, 80-211 Gdansk, Poland.
JF  - Cancer treatment reviews
JA  - Cancer Treat.Rev.
M1  - Journal
ER  - 

TY  - JOUR
ID  - 6390
A1  - Shiraishi,I.
T1  - Applications of multi-slice computed tomography imaging in children with congenital heart diseases
Y1  - 2007
Y2  - Jul
VL  - 60
IS  - 8 Suppl
SP  - 619
EP  - 626
AB  - Recently-devised 3-dimensional (3D) diagnostic modalities such as magnetic resonance imaging and multi-slice computed tomography (MSCT) allow visualization of the heart and great vessels from any angle of view and perspective. Among them, the MSCT examination provides highly contrasted 3D images of complicated congenital heart diseases (CHD) and is now widely used instead of cardiac angiography. Here we introduce several applications of the MSCT examination in children with CHD. The MSCT examinations were performed without electorocardiogram (ECG)-gating in order to minimize radiation exposure. The 3D images of CHDs were exhibited with color-coded reconstruction to visualize clearer images of arteries and veins. The tortuous arteries and veins in the hypoplastic left heart, total anomalous pulmonary venous drainage, pulmonary atresia and ventricular septal defect associated with major aortopulmonary collateral arteries are clearly visualized with non-ECG-gated MSCT, which were very informative for cardiac surgery. We are now trying to make plastic replicas of complicated CHDs by the use of laser stereolithography technique. These replicas can be used for simulations of each surgical operation and for development of novel surgical procedures. The MSCT is a promising tool for the precise diagnosis and planning of surgical operation in complicated CHDs.
N1  - PUBM: Print; JID: 0413533; ppublish
CY  - Japan
A3  - Anonymous
SN  - 0021-5252
AD  - Department of Pediatric Cardiology and Nephrology, Kyoto Prefectural University of Medicine Graduate School of Medical Science, Kyoto, Japan.
JF  - Kyobu geka.The Japanese journal of thoracic surgery
JA  - Kyobu Geka
M1  - Journal
ER  - 

TY  - JOUR
ID  - 6395
A1  - Sinha,A. K.
A1  - Kini,A. S.
A1  - Sharma,S. K.
T1  - Percutaneous valve replacement: a paradigm shift
Y1  - 2007
Y2  - Sep
VL  - 22
IS  - 5
SP  - 471
EP  - 477
AB  - PURPOSE OF REVIEW: Valvular heart disease is often associated with significant morbidity and mortality. Surgical treatment of stenotic or regurgitant valvular lesions can alter the natural history of the disease process, yielding excellent short and long-term results, meaning that this has been accepted as the gold standard for therapy of valvular disease. Surgical procedures can be associated with a significant rate of perioperative complications, however. These procedures are particularly associated with unacceptably high short and long-term morbidity and mortality in the elderly - a population group that has grown steadily over the years. Elderly patients often have significant comorbidities that preclude a safe and durable surgical correction of the valvular lesions in up to 31% of these high-risk cases. This review provides an overview of recent developments in percutaneous valve therapeutics. RECENT FINDINGS: Over the last decade, numerous technical developments in valvular interventions have focused on percutaneous valve replacement. There are percutaneous valve replacements on the horizon that promise to offer a novel approach to correct valvular lesions, especially in this high-risk surgical population. SUMMARY: Several devices are presently being evaluated in feasibility trials, and many new ones are being developed. Results with semilunar valves have generally been better than the atrioventricular valves. Long-term results of these treatment modalities are still unknown.
N1  - PUBM: Print; JID: 8608087; ppublish
CY  - United States
A3  - Anonymous
SN  - 0268-4705
AD  - aKrannert Institute of Cardiology, Indianapolis, USA bThe Zena and Michael A. Wiener Cardiovascular Institute, Mount Sinai Medical Center, New York, USA.
JF  - Current opinion in cardiology
JA  - Curr.Opin.Cardiol.
M1  - Journal
ER  - 

TY  - JOUR
ID  - 6407
A1  - Subramaniam,M.
A1  - Hawse,J. R.
A1  - Johnsen,S. A.
A1  - Spelsberg,T. C.
T1  - Role of TIEG1 in biological processes and disease states
Y1  - 2007
Y2  - Aug 29
AB  - A novel TGFbeta Inducible Early Gene-1 (TIEG1) was discovered in human osteoblast (OB) cells by our laboratory. Over the past decade, a handful of laboratories have revealed a multitude of organismic, cellular, and molecular functions of this gene. TIEG1 is now classified as a member of the 3 zinc finger family of Kruppel-like transcription factors (KLF10). Other closely related factors [TIEG2 (KLF11) and TIEG3/TIEG2b] have been reported and are briefly compared. As described in this review, TIEG1 is shown to play a role in regulating estrogen and TGFbeta actions, the latter through the Smad signaling pathway. In both cases, TIEG1 acts as an inducer or repressor of gene transcription to enhance the TGFbeta/Smad pathway, as well at other signaling pathways, to regulate cell proliferation, differentiation, and apoptosis. This review outlines TIEG1's molecular functions and roles in skeletal disease (osteopenia/osteoporosis), heart disease (hypertrophic cardiomyopathy), and cancer (breast and prostate). J. Cell. Biochem. (c) 2007 Wiley-Liss, Inc.
N1  - PUBM: Print-Electronic; DEP: 20070829; JID: 8205768; aheadofprint
A3  - Anonymous
SN  - 0730-2312
AD  - Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, Rochester, Minnesota.
JF  - Journal of cellular biochemistry
JA  - J.Cell.Biochem.
M1  - Journal
ER  - 

TY  - JOUR
ID  - 6378
A1  - Thrainsdottir,I. S.
A1  - Aspelund,T.
A1  - Gudnason,V.
A1  - Malmberg,K.
A1  - Sigurdsson,G.
A1  - Thorgeirsson,G.
A1  - Hardarson,T.
A1  - Ryden,L.
T1  - Increasing glucose levels and BMI predict future heart failure Experience from the Reykjavik Study
Y1  - 2007
Y2  - Aug 29
AB  - BACKGROUND: Heart failure is common in diabetes and ischaemic heart disease is the most likely link. Still, it has been suggested that the relation extends beyond such disease. METHODS: 7060 subjects with two or more visits in the Reykjavik Study were followed-during 30 years from 1967. All underwent oral glucose tolerance tests. Disease status was defined according to the glycaemic level and presence of heart failure. The incidence and predictive factors for these diseases were determined. FINDINGS: Age and sex standardized incidence of heart failure was 5.3/1000/year, of diabetes 4.6/1000/year and abnormal glucose regulation 12.6/1000/year. Body mass index (BMI) and fasting glucose predicted the development of these conditions (p<0.001). Increasing fasting glucose by 1 mmol/l increased the risk for heart failure by 14% (p=0.04) after adjusting for IHD, BMI and other risk factors for CVD. There was a strong association between diabetes and heart failure, OR 3.0 (2.3-4.0), and abnormal glucose regulation and heart failure, OR 1.8 (1.5-2.3). Diabetes and heart failure were, however, not independent predictors of each other. INTERPRETATION: There was an independent relationship between increases in fasting glucose and development of heart failure. BMI was a strong predictor of heart failure. Although fasting glucose and BMI were significant risk factors for glucose disturbances and heart failure the conditions themselves did not independently predict each other.
N1  - PUBM: Print-Electronic; DEP: 20070829; JID: 100887595; 2006/08/30 [received]; 2007/05/23 [revised]; 2007/07/18 [accepted]; aheadofprint
A3  - Anonymous
SN  - 1388-9842
AD  - Department of Cardiology Karolinska University Hospital Solna, 171 76 Stockholm, Sweden.
JF  - European journal of heart failure : journal of the Working Group on Heart Failure of the European Society of Cardiology
JA  - Eur.J.Heart Fail.
M1  - Journal
ER  - 

TY  - JOUR
ID  - 6391
A1  - Tulumbaci,O.
A1  - Onan,M. A.
A1  - Turkoglu,S.
A1  - Kurdoglu,M.
A1  - Boyaci,B.
A1  - Tiras,M. B.
T1  - Effects of ritodrine hydrochloride tocolysis on echocardiographic parameters
Y1  - 2007
Y2  - Oct
VL  - 20
IS  - 10
SP  - 751
EP  - 755
AB  - Objective. Preterm delivery is a leading cause of perinatal mortality and morbidity. The aim of this study was to determine the effect of ritodrine hydrochloride, used for tocolysis and having serious cardiovascular side effects, on echocardiographic parameters. Methods. Sixty-two pregnant women were included in our study. The study and control groups were composed of patients with preterm labor (group A, N = 30) and patients with uneventful pregnancies (group B, N = 32), respectively. While the patients in group A were evaluated before and during treatment, those in group B were evaluated only once for ejection fraction and fractional shortening of the left side of the heart with echocardiography and for the regional systolic and diastolic functions with the tissue Doppler technique. One-way ANOVA and a t-test (paired comparison) were used for statistical purposes. Results. For the left side of the heart, it was shown that while fractional shortening increased with tocolysis (p  0.05). Conclusions. Due to its potent inotropic and chronotropic effects, ritodrine hydrochloride increases myocardial oxygen demand significantly. Therefore, it should be used sparingly or avoided altogether in patients with ischemic or structural heart disease.
N1  - PUBM: Print; JID: 101136916; ppublish
CY  - United States
A3  - Anonymous
SN  - 1476-7058
AD  - Department of Obstetrics and Gynecology, Yuzuncu Yil Hospital, Ankara, Turkey.
JF  - The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
JA  - J.Matern.Fetal.Neonatal Med.
M1  - Journal
ER  - 

TY  - JOUR
ID  - 6400
A1  - Turk,E. E.
T1  - Natural and traumatic sports-related fatalities: A 10 year retrospective study
Y1  - 2007
Y2  - Aug 30
AB  - OBJECTIVE: to identify the most frequent causes of death during sports activity and to elucidate which groups of sportsmen and sportswomen are particularly in danger of dying during sports and to find out in which types of sport the majority of fatalities occur. DESIGN AND SETTING: we performed a 10 year autopsy-based retrospective study of all 48335 fatalities in Hamburg and the surrounding areas that were subjected to police investigations between 1997 and 2006 and screened for sports-related deaths. MAIN OUTCOME MEASURES: cause of death depending on form of sport, age and risk factors. RESULTS: The vast majority of the deceased were male. In natural deaths, cardiac causes were the most common, with running and football being the most frequent forms of sport. In some of the cases, sports medical examinations had been performed, certifying eligibility for the respective activity. Traumatic deaths were found in all age groups, preferring younger age groups than natural deaths, and expectedly occurred more frequently in "risky" outdoor activities. CONCLUSIONS: Although exercise can have beneficial effects on health, fatalities occur related to sports activity. Cardiac disease is the major cause of sudden death from natural causes. In patients with pre-existing coronary heart disease, left ventricular hypertrophy seems to be a risk factor for exercise-related sudden death. Traumatic deaths often happen on holidays outside the country and are most frequently attributable to drowning and blunt trauma. Preparticipation medical screening can not always prevent fatal incidents during sports activity. Postmortem macroscopic and histologic examination can clarify the cause of death and legal issues.
N1  - PUBM: Print-Electronic; DEP: 20070830; JID: 0432520; aheadofprint
A3  - Anonymous
SN  - 1473-0480
AD  - Institute of Legal Medicine, Germany.
JF  - British journal of sports medicine
JA  - Br.J.Sports Med.
M1  - Journal
ER  - 

TY  - JOUR
ID  - 6374
A1  - Tutschek,B.
A1  - Sahn,D. J.
T1  - Three-Dimensional Echocardiography for Studies of the Fetal Heart: Present Status and Future Perspectives
Y1  - 2007
Y2  - May
VL  - 25
IS  - 2
SP  - 341
EP  - 355
AB  - Three-dimensional (3D) ultrasound of the fetal heart is increasingly being used in prenatal diagnosis. While very detailed fetal cardiac studies can be performed using the various 3D ultrasound modalities, their utility for screening for fetal heart disease is yet to be proven. With the emergence of even newer technologies such as quantification techniques and two-dimensional matrix arrays, further improvements are imminent.
N1  - PUBM: Print; JID: 8300331; ppublish
A3  - Anonymous
SN  - 0733-8651
AD  - Prenatal Medicine Munich, Heinrich Heine University, Lachnerstr 6, 80639 Munchen, Dusseldorf, Germany; Oregon Health & Science University, Pediatric Cardiology Department, Mailcode L608, Portland, OR 97239, USA.
JF  - Cardiology clinics
JA  - Cardiol.Clin.
M1  - Journal
ER  - 

TY  - JOUR
ID  - 6404
A1  - Wan,Q.
A1  - Harris,M. F.
A1  - Powell-Davies,G.
A1  - Jayasinghe,U. W.
A1  - Flack,J.
A1  - Georgiou,A.
A1  - Burns,J. R.
A1  - Penn,D. L.
T1  - Cardiovascular risk levels in general practice patients with type 2 diabetes in rural and urban areas
Y1  - 2007
Y2  - Oct
VL  - 15
IS  - 5
SP  - 327
EP  - 333
AB  - Objective: To investigate the change of cardiovascular risk factor from 2000 to 2002 in general practice patients with type 2 diabetes in urban and rural areas, and the association between cardiovascular risk (both single risk factors and coronary heart disease absolute risk (CHDAR)) and rurality in three years. Methods: In total, 6305 patients were extracted from 16 Divisions (250 practices). Multivariate regression at Division, practice and patient levels was conducted with adjustment for age and gender. Results: In each of the three years, most single individual risk factors and CHDAR were high. Comparing 2002 with 2000: for urban patients in 2002 total cholesterol (OR 0.85) and low-density lipoprotein (OR 0.81) significantly decreased, and high-density lipoprotein (HDL) (OR 1.16) significantly increased; for rural patients in 2002 HbA1c (OR 0.85) significantly decreased and HDL (OR 1.22) significantly increased; and CHDAR significantly improved only in urban patients (OR 0.93) in 2002. In 2002 rural patients were still more likely to be overweight/obese (OR 1.16), be current smokers (OR 1.36), and have worse HDL (OR 0.84) and triglycerides (OR 1.23) than their urban counterparts. Conclusion: Some key individual risk factors and CHDAR did not improve in rural patients with type 2 diabetes despite a number of programs designed to provide comprehensive care to rural patients with diabetes. More emphasis is needed on supporting access to lifestyle changes (such as smoking, diet and physical activity) in rural primary health care.
N1  - PUBM: Print; JID: 9305903; ppublish
CY  - Australia
A3  - Anonymous
SN  - 1038-5282
AD  - Centre for Primary Health Care and Equity, School of Public Health and Community Medicine, University of New South Wales, Sydney, New South Wales, Australia.
JF  - The Australian Journal of Rural Health
JA  - Aust.J.Rural Health
M1  - Journal
ER  - 

TY  - JOUR
ID  - 6393
A1  - Wong,C. F.
A1  - McCarthy,M.
A1  - Howse,M. L.
A1  - Williams,P. S.
T1  - Factors affecting survival in advanced chronic kidney disease patients who choose not to receive dialysis
Y1  - 2007
VL  - 29
IS  - 6
SP  - 653
EP  - 659
AB  - Introduction. Non-dialytic treatment (NDT) has become a recognized and important modality of treatment in end stage renal disease (ESRD) in certain groups of chronic kidney disease (CKD) patients. However, little is known about the prognosis of these NDT patients in terms of hospitalization rates and survival. We analyzed our experience in managing these NDT with a multidisciplinary team (MDT) approach over a three-year period. Patients and Methods. The Renal Unit at the Royal Liverpool University Hospital set up a dedicated MDT clinic to manage NDT patients in January 2003. Patients approaching end stage chronic kidney disease who chose not to dialyse were recruited from other nephrologists. The study group was classified according to age band (80 years), estimated glomerular filtration rate (eGFR) (20 ml/min) according to the Modified Diet In Renal Disease formula and Stoke comorbidity grade (SCG). The SCG is a validated scoring system for the survival of patients on renal replacement therapy. We also used the ERA-EDTA primary renal diagnosis codes. As there are no existing standards for NDT patients, we used the U.K. national set for haemodialysis patients as a reference and target for our NDT patients. Data was collected prospectively. Results. The median age was 79 years and the male: female ratio was approximately 1. The most common primary cause of kidney disease in the NDT study population was chronic renal failure of unknown cause n = 22 (31%), but the most common identifiable cause was diabetic nephropathy, n = 20 (28%). The most common comorbidity was ischaemic heart disease n = 25 (34%). Those achieving the standards for anaemia were 78% at referral. Only 30% of the NDT patients achieved the standard for blood pressure (<130/80 mmHg) at referral. Forty-three patients (60%) had no admissions at all. There were a total of 30 patients admitted on 58 occasions. Thirty-one (53%) of these were due to a non-renal cause. The median length of stay for the other NDT patients was 10 days. The median overall survival (life expectancy) was 1.95 years. The one-year overall survival was 65%. SCG was an independent prognostic factor in predicting survival in NDT patients studied (p = 0.005), the hazard ratio being 2.53, for each incremental increase in the SCG. At one year, the survival for comorbidity grade 0, 1 and 2 were 83%, 70% and 56% respectively. Of the 28 patients who died, 20 did so at home (71%). Discussion. The NDT of ESRD has become an important alternative modality in renal replacement therapy. With the emergence of epidemic proportions of CKD, more elderly patients with progressive renal disease will need to make informed decisions regarding renal replacement therapy. There is likely to be increasing number of elderly patients that will tolerate dialysis badly and who will be very dependent on others. We believe that there should be a multidisciplinary approach to assist the ESRD patients in choosing their modality of renal replacement therapy, and with an agreed care plan to support these patients in managing their chosen modality to achieve the best possible quality of life. There should be integrated services with primary care, community nurses, and palliative care teams to enable the majority of the patient's treatment to be carried out at home and to allow a dignified death. However. there was a statistically significant trend for shorter survival among those with greater comorbidities, as determined by the SCG. This is the first report of the potential importance of SCG as an independent prognostic factor in NDT patients. This will help us to counsel our patients in the future about their prognosis if they choose NDT as their modality of renal replacement therapy. Conclusion. Our prospective study is the first and currently the largest observational study of a multidisciplinary approach in the management of NDT patients. SCG was an independent prognostic factor in predicting survival. In those patients who chose not to dialyse, SCG provides a potentially useful indication of expected prognosis.
N1  - PUBM: Print; JID: 8701128; ppublish
CY  - United States
A3  - Anonymous
SN  - 0886-022X
AD  - Department of Nephrology, Aintree University Hospital Foundation Trust, Liverpool, UK.
JF  - Renal failure
JA  - Ren.Fail.
M1  - Journal
ER  - 

TY  - JOUR
ID  - 6402
A1  - Youssef,M. Y.
A1  - Mojiminiyi,O. A.
A1  - Abdella,N. A.
T1  - Plasma concentrations of C-reactive protein and total homocysteine in relation to the severity and risk factors for cerebrovascular disease
Y1  - 2007
Y2  - Sep
VL  - 150
IS  - 3
SP  - 158
EP  - 163
AB  - Higher C-reactive protein (CRP) and plasma homocysteine (tHcy) concentrations have been shown to indicate increased risk of coronary heart disease and cerebrovascular disease (CVD), but the mechanisms by which they increase the risk of atherothrombotic disease are under investigation. This study evaluates the associations of high-sensitivity C-reactive protein (hs-CRP) and tHcy with the risk factors, severity, and outcome on discharge in patients with CVD. hs-CRP, fasting tHcy, and lipid profile were determined in 50 patients with CVD and 20 healthy control subjects. Clinical data, National Institutes of Health stroke scale (NIHSS) on admission and disability Rankin scale on discharge, were recorded. Based on epidemiologic studies, cutoff points of 1.5 mg/L (hs-CRP) and 15mumol/L (tHcy) were used to indicate increased risk. Univariate and multivariate logistic regression analyses were used to relate tHcy with other CVD risk factors, NIHSS on admission and the disability Rankin scale on discharge. Overall, 38% of patients had increased hs-CRP and 26% had elevated tHcy. hs-CRP (P = 0.005) and tHcy (P < 0.0001) concentrations were significantly higher in patients compared with controls, and these differences remained significant after correction for age and sex. tHcy showed significant correlations with hs-CRP (rs = 0.35; P = 0.003) and low-density lipoprotein-cholesterol (LDL-C; rs = 0.49; P = 0.005). Logistic regression analysis with CVD as the dependent variable showed significant association with hs-CRP (P = 0.01) and tHcy (P < 0.0001) after adjustment for potential confounders. hs-CRP showed increased trend with disease severity and significant association with the disability Rankin scale (P = 0.033). These data support 4 main conclusions: (1) Elevation of hs-CRP and tHcy are common in CVD; (2) the significant relationship between tHcy and hs-CRP suggests that the association of tHcy with CVD risk may be dependent on inflammation-related mechanisms; (3) increased hs-CRP and tHcy show that patients with CVD may be at greater risk of subsequent coronary heart disease; and (4) admission hs-CRP could be used as an indicator of prognosis.
N1  - PUBM: Print-Electronic; DEP: 20070525; JID: 101280339; 2006/09/18 [received]; 2007/02/11 [revised]; 2007/02/14 [accepted]; 2007/05/25 [aheadofprint]; ppublish
CY  - United States
A3  - Anonymous
SN  - 1931-5244
AD  - Ministry of Health, Faculty of Medicine, Kuwait University, Safat, Kuwait.
JF  - Translational research : the journal of laboratory and clinical medicine
JA  - Transl.Res.
M1  - Journal
ER  -